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Ube2e3 Gene Detail
Summary
  • Symbol
    Ube2e3
  • Name
    ubiquitin-conjugating enzyme E2E 3
  • Synonyms
    Ubce4, ubcM2
  • Feature Type
    protein coding gene
  • IDs
    MGI:107412
    NCBI Gene: 22193
  • Gene Overview
    MyGene.info: UBE2E3
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:78868243-78921288 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 47.15 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    185 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107412
protein coding gene Chr2:78868124-78921293 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025875
protein coding gene Chr2:79358577-79420022 (+)
A/J MGP_AJ_G0025852
protein coding gene Chr2:76308512-76364717 (+)
AKR/J MGP_AKRJ_G0025821
protein coding gene Chr2:78308737-78363731 (+)
BALB/cJ MGP_BALBcJ_G0025848
protein coding gene Chr2:76442234-76495804 (+)
C3H/HeJ MGP_C3HHeJ_G0025607
protein coding gene Chr2:78530431-78586833 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026294
protein coding gene Chr2:81703654-81760248 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023697
protein coding gene Chr2:73588845-73642088 (+)
CAST/EiJ MGP_CASTEiJ_G0025069
protein coding gene Chr2:78951804-79011685 (+)
CBA/J MGP_CBAJ_G0025588
protein coding gene Chr2:84638579-84699292 (+)
DBA/2J MGP_DBA2J_G0025719
protein coding gene Chr2:75867585-75921655 (+)
FVB/NJ MGP_FVBNJ_G0025681
protein coding gene Chr2:75240645-75293637 (+)
LP/J MGP_LPJ_G0025807
protein coding gene Chr2:79248087-79308875 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025712
protein coding gene Chr2:86521155-86580602 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026350
protein coding gene Chr2:78471754-78529636 (+)
PWK/PhJ MGP_PWKPhJ_G0024812
protein coding gene Chr2:75810738-75867643 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024618
protein coding gene Chr2:78751259-78806723 (+)
WSB/EiJ MGP_WSBEiJ_G0025138
protein coding gene Chr2:79093041-79148258 (+)



Homology
more
  • Human Ortholog
    UBE2E3, ubiquitin conjugating enzyme E2 E3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UBE2E3, ubiquitin conjugating enzyme E2 E3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    UBCH9, UbcM2
  • Links
    NCBI Gene ID: 10477
    neXtProt AC: NX_Q969T4
    UniProt: Q969T4

  • Chr Location
    2q31.3; chr2:180980381-181063427 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22193 NCBI Gene Model | MGI Sequence Detail 53046 C57BL/6J ±  kb
transcript NR_151457 RefSeq | MGI Sequence Detail 2731 C57BL/6  
polypeptide P52483 UniProt | EBI | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-35881
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:31581 Matuschewski K, et al., Identification of a novel family of ubiquitin-conjugating enzymes with distinct amino-terminal extensions. J Biol Chem. 1996 Feb 2;271(5):2789-94
  • Latest
    J:227263 Fabre PJ, et al., Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13964-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory