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Zbtb17
Gene Detail
 Symbol
Name
ID
Zbtb17
zinc finger and BTB domain containing 17
MGI:107410
Synonyms Miz1, mZ13, Zfp100
Feature Type protein coding gene
Genetic Map
Chromosome 4
74.17 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:141444654-141467930 bp, + strand
From VEGA annotation of GRCm38

  23277 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2575  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Zbtb17

Human
homologs
Human Homolog ZBTB17, zinc finger and BTB domain containing 17
NCBI Gene ID 7709
neXtProt AC  NX_Q13105
Human Synonyms  MIZ-1, pHZ-67, ZNF151, ZNF60
Human Chr (Location)  1p36.13; chr1:15941869-15976132 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(28) : Gene trapped(25) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Embryonic development of homozygous null mice is severely impaired and death occurs prior to E8.5.
 
Interactions
Zbtb17 interacts with 40 markers (Mir96, Mir154, Mir191, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process ectoderm development, gastrulation with mouth forming second, ...
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (57)    Tissues (57)    Images (4)
Theiler Stages: 2, 3, 4, 5, 15, 17, 18, 19, 21, 23, 27, 28
Assay TypeResults
RNA in situ 49
RT-PCR 8
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) Genomic(1) cDNA(10) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000010292 (Evidence)
Ensembl Gene ModelENSMUSG00000006215 (Evidence)
Entrez Gene22642 (Evidence)
DoTSDT.101223921, DT.101387070, DT.490521, DT.94154457, DT.94302359
NIA Mouse Gene IndexU005042
Consensus CDS ProjectCCDS18875.1
International Mouse Knockout Project StatusZbtb17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010292 VEGA Gene Model | MGI Sequence Detail 23277 C57BL/6J ±  kb
transcript OTTMUST00000023959 VEGA | MGI Sequence Detail 2722 Not Applicable 
polypeptide OTTMUSP00000010988 VEGA | MGI Sequence Detail 794 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(355 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013069 BTB/POZ
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017566 zinc finger and BTB domain-containing protein 17
References (Earliest) J:29058 Schulz TC, et al., An unusual arrangement of 13 zinc fingers in the vertebrate gene Z13. Biochem J. 1995 Oct 1;311(Pt 1):219-24
(Latest) J:206009 Wolf E, et al., Miz1 is required to maintain autophagic flux. Nat Commun. 2013;4:2535
All references(53)
Other
accession IDs
MGD-MRK-35879, MGI:2140165

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory