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Il17ra
Gene Detail
 Symbol
Name
ID
Il17ra
interleukin 17 receptor A
MGI:107399
Synonyms Il17r, VDw217
Feature Type protein coding gene
Genetic Map
Chromosome 6
56.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr6:120463197-120483727 bp, + strand
From NCBI annotation of GRCm38

  20531 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7378  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Il17ra

Human
homologs
Human Homolog IL17RA, interleukin 17 receptor A
NCBI Gene ID 23765
neXtProt AC  NX_Q96F46
Human Synonyms  CANDF5, CD217, CDw217, hIL-17R, IL17R, IL-17RA
Human Chr (Location)  22q11.1; chr22:17084959-17115694 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human IL17RA
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
 
Homozygotes for a targeted null mutation exhibit delayed neutrophil recruitment and enhanced susceptibility to intranasal infection by Klibsiella pneumoniae. Mice homozygous for a different knock-out allele exhibit delayed and milder IMQ-induced psoriasis.
 
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process cellular response to cytokine stimulus, fibroblast activation, ...
Component integral component of membrane, membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (5)    Tissues (1)    Images (5)
Theiler Stages: 23
Assay TypeResults
RNA in situ 5
cDNA source data(56)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(59) cDNA(57) Other(2)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000002897 (Evidence)
Entrez Gene16172 (Evidence)
UniGene4481
DFCITC1581495, TC1583055, TC1599393
DoTSDT.101335937, DT.529054
NIA Mouse Gene IndexU007342
Consensus CDS ProjectCCDS20482.1
International Mouse Knockout Project StatusIl17ra
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16172 NCBI Gene Model | MGI Sequence Detail 20531 C57BL/6J ±  kb
transcript NM_008359 RefSeq | MGI Sequence Detail 3970 C57BL/6 
polypeptide Q60943 UniProt | EBI | MGI Sequence Detail 864 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(6) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(68 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013568 SEFIR
Protein Ontology PR:000001375 interleukin-17 receptor A
Graphical View of Protein Domain Structure
References (Earliest) J:30252 Yao Z, et al., Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity. 1995 Dec;3(6):811-21
(Latest) J:205037 Gopal R, et al., Mucosal pre-exposure to Th17-inducing adjuvants exacerbates pathology after influenza infection. Am J Pathol. 2014 Jan;184(1):55-63
All references(137)
Other
accession IDs
MGD-MRK-35866, MGI:2141691

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory