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Il17ra
Gene Detail
Symbol

Name
ID
Il17ra
interleukin 17 receptor A
MGI:107399
Synonyms
Il17r, VDw217
Feature Type
protein coding gene
Genetic Map
Chromosome 6
56.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr6:120463197-120483727 bp, + strand
From Ensembl annotation of GRCm38

  20531 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7378  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Il17ra

Human
homologs
Human Homolog IL17RA, interleukin 17 receptor A
NCBI Gene ID 23765
neXtProt AC  NX_Q96F46
Human Synonyms  CANDF5, CD217, CDw217, hIL-17R, IL17R, IL-17RA
Human Chr (Location)  22q11.1; chr22:17084959-17115694 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human IL17RA
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a targeted null mutation exhibit delayed neutrophil recruitment and enhanced susceptibility to intranasal infection by Klibsiella pneumoniae. Mice homozygous for a different knock-out allele exhibit delayed and milder IMQ-induced psoriasis.
 
Interactions
Il17ra interacts with 194 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (5)    Tissues (1)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 5
cDNA source data(56)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(59) cDNA(57) Other(2)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000002897 (Evidence)
Entrez Gene16172 (Evidence)
UniGene4481
DFCITC1599393, TC1583055, TC1581495
DoTSDT.101335937, DT.529054
NIA Mouse Gene IndexU007342
Consensus CDS ProjectCCDS20482.1
International Mouse Knockout Project StatusIl17ra
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002897 Ensembl Gene Model | MGI Sequence Detail 20531 C57BL/6J ±  kb
transcript ENSMUST00000002976 Ensembl | MGI Sequence Detail 3970 Not Applicable 
polypeptide ENSMUSP00000002976 Ensembl | MGI Sequence Detail 864 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(6) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(68 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013568 SEFIR
Protein Ontology PR:000001375 interleukin-17 receptor A
References
(Earliest) J:30252 Yao Z, et al., Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity. 1995 Dec;3(6):811-21
(Latest) J:212190 Ge S, et al., Interleukin 17 receptor A modulates monocyte subsets and macrophage generation in vivo. PLoS One. 2014;9(1):e85461
All references(148)
Other
accession IDs
MGD-MRK-35866, MGI:2141691

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory