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Ing4
Gene Detail
 Symbol
Name
ID
Ing4
inhibitor of growth family, member 4
MGI:107307
Synonyms D6Wsu147e, D6Xrf92, p29ING4
Feature Type protein coding gene
Genetic Map
Chromosome 6
59.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr6:125039760-125051499 bp, + strand
From VEGA annotation of GRCm38

  11740 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22952  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: uncharacterized conserved protein
Gene Tree: Ing4

Human
homologs
Human Homolog ING4, inhibitor of growth family, member 4
NCBI Gene ID 51147
neXtProt AC  NX_Q9UNL4
Human Synonyms  my036, p29ING4
Human Chr (Location)  12p13.31; chr12:6650538-6663142 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(19) : Gene trapped(19)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trapped allele are hypersensitive to LPS challenge and exhibit elevated cytokine responses.
 
Interactions
Ing4 interacts with 295 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process apoptotic process, cell cycle, ...
Component histone acetyltransferase complex, nucleus
Function metal ion binding, methylated histone binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (195)    Tissues (96)    Images (27)
Theiler Stages: 2, 3, 4, 5, 11, 16, 17, 21, 22, 23, 27, 28
Assay TypeResults
RNA in situ 181
RT-PCR 14
cDNA source data(165)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(169) cDNA(166) Primer pair(2) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000024325 (Evidence)
Ensembl Gene ModelENSMUSG00000030330 (Evidence)
Entrez Gene28019 (Evidence)
UniGene262547
DFCITC1574387, TC1600706, TC1650124, TC1676904, TC1730389, TC1778391
DoTSDT.101127377, DT.101288599, DT.101393876, DT.101738353, DT.534690, DT.91552919, DT.99861590
PDB1WEN, 1WEU
Consensus CDS ProjectCCDS39632.1
International Mouse Knockout Project StatusIng4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024325 VEGA Gene Model | MGI Sequence Detail 11740 C57BL/6J ±  kb
transcript OTTMUST00000059581 VEGA | MGI Sequence Detail 1446 Not Applicable 
polypeptide OTTMUSP00000028995 VEGA | MGI Sequence Detail 249 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(3) UniProt(1)
Polymorphisms SNPs within 2kb(61 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024610 Inhibitor of growth protein, N-terminal
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000009036 inhibitor of growth protein 4
References (Earliest) J:31523 Bassett DE Jr, et al., Comparative genomics, genome cross-referencing and XREFdb. Trends Genet. 1995 Sep;11(9):372-3
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(45)
Other
accession IDs
MGD-MRK-32273, MGD-MRK-35773, MGI:105232

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory