About   Help   FAQ
Cyp2b19
Gene Detail
 Symbol
Name
ID
Cyp2b19
cytochrome P450, family 2, subfamily b, polypeptide 19
MGI:107303
Feature Type protein coding gene
Genetic Map
Chromosome 7
15.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:26757163-26772630 bp, + strand
From VEGA annotation of GRCm38

  15468 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:104114  Vertebrate Homology Class
1 mouse; 3 rat

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2b19

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Cyp2b19 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp2b19 interacts with 171 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function arachidonic acid epoxygenase activity, aromatase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (116)    Tissues (96)    Images (24)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 116
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027196 (Evidence)
Ensembl Gene ModelENSMUSG00000066704 (Evidence)
Entrez Gene13090 (Evidence)
UniGene14098
DFCITC1628771, TC1655383
DoTSDT.101716621, DT.524734
NIA Mouse Gene IndexU007839
EC1.14.14.1
Consensus CDS ProjectCCDS21006.1
International Mouse Knockout Project StatusCyp2b19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027196 VEGA Gene Model | MGI Sequence Detail 15468 C57BL/6J ±  kb
transcript OTTMUST00000067245 VEGA | MGI Sequence Detail 2719 Not Applicable 
polypeptide OTTMUSP00000033807 VEGA | MGI Sequence Detail 492 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(8) UniProt(1)
Polymorphisms RFLP(1) : SNPs within 2kb(150 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008068 Cytochrome P450, E-class, group I, CYP2B-like
Protein Ontology PR:000006223 cytochrome P450 2B19
References (Earliest) J:45291 Keeney DS, The novel skin-specific cytochrome p450 Cyp2b19 maps to proximal chromosome 7 in the mouse, near a cluster of Cyp2 family genes. Genomics. 1998 NOV 1;53(3):417-419
(Latest) J:183667 Damiri B, et al., Lentiviral-mediated RNAi knockdown yields a novel mouse model for studying Cyp2b function. Toxicol Sci. 2012 Feb;125(2):368-81
All references(29)
Other
accession IDs
MGD-MRK-35769

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/23/2014
MGI 5.19
The Jackson Laboratory