Cyp2b19
Gene Detail

Symbol Name ID

Cyp2b19 cytochrome P450, family 2, subfamily b, polypeptide 19 MGI:107303

Feature Type

protein coding gene

Genetic Map

Chromosome 7

15.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:26757163-26772630 bp, + strand From VEGA annotation of GRCm38   15468 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:104114  Vertebrate Homology Class
1 mouse; 2 rat

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2b19

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	oxidation-reduction process
Component	endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function	arachidonic acid epoxygenase activity, aromatase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (116)    Tissues (96)    Images (24)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	116

cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(13) cDNA(12) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000027196 (Evidence)
Ensembl Gene Model	ENSMUSG00000066704 (Evidence)
Entrez Gene	13090 (Evidence)
UniGene	14098
DFCI	TC1628771, TC1655383
DoTS	DT.101716621, DT.524734
NIA Mouse Gene Index	U007839
EC	1.14.14.1
Consensus CDS Project	CCDS21006.1
International Mouse Knockout Project Status	Cyp2b19

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027196	VEGA Gene Model | MGI Sequence Detail	15468	C57BL/6J
transcript	OTTMUST00000067245	VEGA | MGI Sequence Detail	2719	Not Applicable
polypeptide	OTTMUSP00000033807	VEGA | MGI Sequence Detail	492	Not Applicable

All sequences(24) RefSeq(2) UniProt(1)

Polymorphisms

RFLP(1) : SNPs(136 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
InterPro	IPR008068	Cytochrome P450, E-class, group I, CYP2B-like
Protein Ontology	PR:000006223	cytochrome P450 2B19

References

(Earliest) J:45291 Keeney DS, The novel skin-specific cytochrome p450 Cyp2b19 maps to proximal chromosome 7 in the mouse, near a cluster of Cyp2 family genes. Genomics. 1998 NOV 1;53(3):417-419
(Latest) J:183667 Damiri B, et al., Lentiviral-mediated RNAi knockdown yields a novel mouse model for studying Cyp2b function. Toxicol Sci. 2012 Feb;125(2):368-81
All references(29)

Other accession IDs

MGD-MRK-35769