About   Help   FAQ
Ubfd1 Gene Detail
Summary
  • Symbol
    Ubfd1
  • Name
    ubiquitin family domain containing 1
  • Synonyms
    D7Wsu105e, D7Wsu128e
  • Feature Type
    protein coding gene
  • IDs
    MGI:107301
    NCBI Gene: 28018
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:121666398-121681417 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 65.35 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    308 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107301
 protein coding gene Chr7:121666318-121681422 (+)
129S1/SvImJ ENSMUSG00200022159
 protein coding gene Chr7:108187593-108202624 (+)
A/J ENSMUSG00195033579
 protein coding gene Chr7:112724134-112739148 (+)
AKR/J ENSMUSG00220018636
 protein coding gene Chr7:106148556-106163575 (+)
BALB/cJ ENSMUSG00180025742
 protein coding gene Chr7:109379475-109394494 (+)
C3H/HeJ ENSMUSG00175021324
 protein coding gene Chr7:110092799-110107818 (+)
C57BL/6NJ ENSMUSG00215033632
 protein coding gene Chr7:109342813-109357831 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030415
 protein coding gene Chr7:124187729-124202881 (+)
CAST/EiJ ENSTCUG00005047448
 protein coding gene Chr7:112658477-112673491 (+)
CBA/J ENSMUSG00210023862
 protein coding gene Chr7:109820375-109835394 (+)
DBA/2J ENSMUSG00185038512
 protein coding gene Chr7:114166511-114181530 (+)
FVB/NJ ENSMUSG00205023607
 protein coding gene Chr7:109826804-109841823 (+)
JF1/MsJ ENSUMUG00000050031
 protein coding gene Chr7:119250012-119265006 (+)
LP/J ENSMUSG00230033064
 protein coding gene Chr7:120275400-120290431 (+)
NOD/ShiLtJ ENSMUSG00190019936
 protein coding gene Chr7:110019466-110034485 (+)
NZO/HlLtJ ENSMUSG00225038758
 protein coding gene Chr7:118525061-118540091 (+)
PWK/PhJ ENSLUMG00010012658
 protein coding gene Chr7:108360017-108375036 (+)
SPRET/EiJ ENSMSPG00010007951
 protein coding gene Chr7:109586735-109601697 (+)
WSB/EiJ ENSIUOG00005011375
 protein coding gene Chr7:110715379-110730420 (+)



Homology
more
  • Human Ortholog
    UBFD1, ubiquitin family domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBFD1, ubiquitin family domain containing 1
  • Synonyms
    UBPH
  • Links
    NCBI Gene ID: 56061
    UniProt: O14562

  • Chr Location
    16p12.2; chr16:23557721-23574394 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    609
  • Tissues
    2
  • cDNA Data
    17
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030870 Ensembl Gene Model | MGI Sequence Detail 15020 C57BL/6J ±  kb
transcript ENSMUST00000033158 Ensembl | MGI Sequence Detail 4849 Not Applicable  
polypeptide ENSMUSP00000033158 Ensembl | MGI Sequence Detail 368 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 17
    Primer pair 2

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-34143, MGD-MRK-35767, MGI:106449, MGI:2141978
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Phenotypes 8
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:385286 McLelland GL, et al., Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. Elife. 2018 Apr 20;7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory