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Rab6b
Gene Detail
 Symbol
Name
ID
Rab6b
RAB6B, member RAS oncogene family
MGI:107283
Synonyms C330006L04Rik, D9Bwg0185e
Feature Type protein coding gene
Genetic Map
Chromosome 9
54.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:103112074-103185270 bp, + strand
From NCBI annotation of GRCm38

  73197 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:39749  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab6b

Human
homologs
Human Homolog RAB6B, RAB6B, member RAS oncogene family
NCBI Gene ID 51560
neXtProt AC  NX_Q9NRW1
Human Chr (Location)  3q22.1; chr3:133824235-133895847 (-)  GRCh38
Alleles
and
phenotypes
All alleles(8) : Gene trapped(8)
 
Homozygous mutation of this gene results in growth retardation and multiple behavioral and immunological abnormalities.
 
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process protein transport, small GTPase mediated signal transduction, ...
Component cytoplasmic vesicle, Golgi apparatus, ...
Function GTP binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (105)    Tissues (27)    Images (23)
Theiler Stages: 17, 21, 23, 24, 26, 28
Assay TypeResults
RNA in situ 93
Western blot 12
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(8)
Other database
links
Ensembl Gene ModelENSMUSG00000032549 (Evidence)
Entrez Gene270192 (Evidence)
DFCITC1575875, TC1621027
DoTSDT.488158
NIA Mouse Gene IndexU010941
Consensus CDS ProjectCCDS23449.1
International Mouse Knockout Project StatusRab6b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 270192 NCBI Gene Model | MGI Sequence Detail 73197 C57BL/6J ±  kb
transcript NM_173781 RefSeq | MGI Sequence Detail 4734 C57BL/6 
polypeptide P61294 UniProt | EBI | MGI Sequence Detail 208 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(505 from dbSNP Build 137)    SNPs within 2kb including multiple locations(507)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013637 ras-related protein Rab-6B
Graphical View of Protein Domain Structure
References (Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)
Other
accession IDs
MGD-MRK-35748, MGI:1924738, MGI:2143137

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory