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Rab6b
Gene Detail
Symbol

Name
ID
Rab6b
RAB6B, member RAS oncogene family
MGI:107283
Synonyms
C330006L04Rik, D9Bwg0185e
Feature Type
protein coding gene
Genetic Map
Chromosome 9
54.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:103111787-103185276 bp, + strand
From VEGA annotation of GRCm38

  73490 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:39749  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAB6B
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab6b

Human
homologs
RAB6B, RAB6B, member RAS oncogene family
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 51560
neXtProt AC: NX_Q9NRW1

Human Chr (Location): 3q22.1; chr3:133824235-133895847 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(8)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in growth retardation and multiple behavioral and immunological abnormalities.
 
Interactions
Rab6b interacts with 388 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process intracellular protein transport, intra-Golgi vesicle-mediated transport, ...
Component cytoplasmic vesicle, Golgi apparatus, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (105)    Tissues (27)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 93
Western blot 12
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rab6b ; ZFIN zgc:112018    NEW 
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000048481 (Evidence)
Ensembl Gene Model ENSMUSG00000032549 (Evidence)
Entrez Gene 270192 (Evidence)
DFCI TC1575875, TC1621027
DoTS DT.488158
NIA Mouse Gene Index U010941
Consensus CDS Project CCDS23449.1
International Mouse Phenotyping Consortium Status Rab6b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048481 VEGA Gene Model | MGI Sequence Detail 73490 C57BL/6J ±  kb
transcript OTTMUST00000124253 VEGA | MGI Sequence Detail 5007 Not Applicable 
polypeptide OTTMUSP00000067645 VEGA | MGI Sequence Detail 208 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(505 from dbSNP Build 137)    SNPs within 2kb including multiple locations(507)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013637 ras-related protein Rab-6B
References
(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)
Other
accession IDs
MGD-MRK-35748, MGI:1924738, MGI:2143137

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory