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Lsg1 Gene Detail
Summary
  • Symbol
    Lsg1
  • Name
    large 60S subunit nuclear export GTPase 1
  • Synonyms
    D16Bwg1547e
  • Feature Type
    protein coding gene
  • IDs
    MGI:107236
    NCBI Gene: 224092
  • Gene Overview
    MyGene.info: LSG1
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:30561369-30587613 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 21.34 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    179 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107236
protein coding gene Chr16:30560494-30587613 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022714
protein coding gene Chr16:28470817-28501863 (-)
A/J MGP_AJ_G0022677
protein coding gene Chr16:27163341-27191218 (-)
AKR/J MGP_AKRJ_G0022651
protein coding gene Chr16:28191583-28218604 (-)
BALB/cJ MGP_BALBcJ_G0022681
protein coding gene Chr16:27336439-27363878 (-)
C3H/HeJ MGP_C3HHeJ_G0022446
protein coding gene Chr16:28294295-28322080 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023130
protein coding gene Chr16:29088674-29116807 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020648
protein coding gene Chr16:27595133-27622576 (-)
CAST/EiJ MGP_CASTEiJ_G0021974
protein coding gene Chr16:28392180-28421005 (-)
CBA/J MGP_CBAJ_G0022416
protein coding gene Chr16:30323192-30350261 (-)
DBA/2J MGP_DBA2J_G0022549
protein coding gene Chr16:27038432-27065513 (-)
FVB/NJ MGP_FVBNJ_G0022524
protein coding gene Chr16:27016630-27044069 (-)
LP/J MGP_LPJ_G0022616
protein coding gene Chr16:28292357-28319466 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022543
protein coding gene Chr16:29817213-29845248 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023142
protein coding gene Chr16:28149598-28178926 (-)
PWK/PhJ MGP_PWKPhJ_G0021713
protein coding gene Chr16:27348907-27376757 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021544
protein coding gene Chr16:27909132-27938896 (-)
WSB/EiJ MGP_WSBEiJ_G0022018
protein coding gene Chr16:28095877-28125544 (-)



Homology
more
  • Human Ortholog
    LSG1, large 60S subunit nuclear export GTPase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LSG1, large 60S subunit nuclear export GTPase 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55341
    neXtProt AC: NX_Q9H089
    UniProt: Q9H089

  • Chr Location
    3q29; chr3:194640788-194672477 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 5917
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LSG1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 224092 NCBI Gene Model | MGI Sequence Detail 26245 C57BL/6J ±  kb
transcript NM_178069 RefSeq | MGI Sequence Detail 2373 FVB/N  
polypeptide Q3UM18 UniProt | EBI | MGI Sequence Detail 644 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    cDNA 65
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-35701, MGI:2146341
References
more
  • Summaries
    All 29
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory