Gtf2h5
Gene Detail

Symbol Name ID

Gtf2h5 general transcription factor IIH, polypeptide 5 MGI:107227

Synonyms

2700017P07Rik, 2810432H05Rik, D17Wsu155e

Feature Type

protein coding gene

Genetic Map

Chromosome 17

3.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr17:6079786-6086517 bp, + strand From VEGA annotation of GRCm38   6732 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:45635  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Gtf2h5

Human homologs

Human Homolog		GTF2H5, general transcription factor IIH, polypeptide 5
NCBI Gene ID		404672
neXtProt AC		NX_Q6ZYL4
Human Synonyms		bA120J8.2, C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTDA, TTD-A
Human Chr (Location)		6q25.3; chr6:158589379-158620376 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human GTF2H5

Alleles and phenotypes

All alleles(16) : Gene trapped(16)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	DNA repair, nucleotide-excision repair, ...
Component	core TFIIH complex, nucleus
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (292)    Tissues (30)    Images (45)
Theiler Stages: 3, 11, 23

Assay Type	Results
RNA in situ	274
RT-PCR	18

cDNA source data(70)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(75) cDNA(71) Primer pair(3) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000024049 (Evidence)
Ensembl Gene Model	ENSMUSG00000034345 (Evidence)
Entrez Gene	66467 (Evidence)
UniGene	303441
DFCI	TC1576253, TC1621811
DoTS	DT.101715961, DT.55100842
NIA Mouse Gene Index	U037366
Consensus CDS Project	CCDS37423.1
International Mouse Knockout Project Status	Gtf2h5

Sequences

Length	Strain/Species
genomic	OTTMUSG00000024049	VEGA Gene Model | MGI Sequence Detail	6732	C57BL/6J
transcript	OTTMUST00000058798	VEGA | MGI Sequence Detail	2245	Not Applicable
polypeptide	OTTMUSP00000028538	VEGA | MGI Sequence Detail	71	Not Applicable

All sequences(32) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(15 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009400	TFIIH subunit TTDA/Tfb5
Protein Ontology	PR:000008321	general transcription factor IIH subunit 5

References

(Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:181994 Kamileri I, et al., Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2995-3000
All references(34)

Other accession IDs

MGD-MRK-35692, MGI:1913717, MGI:1919816