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Cct7 Gene Detail
Summary
  • Symbol
    Cct7
  • Name
    chaperonin containing Tcp1, subunit 7 (eta)
  • Synonyms
    Ccth, Cctz
  • Feature Type
    protein coding gene
  • IDs
    MGI:107184
    NCBI Gene: 12468
  • Gene Overview
    MyGene.info: CCT7
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:85451514-85468475 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.46 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107184
protein coding gene Chr6:85451505-85468477 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030955
protein coding gene Chr6:86618138-86636294 (+)
A/J MGP_AJ_G0030924
protein coding gene Chr6:83320322-83338513 (+)
AKR/J MGP_AKRJ_G0030852
protein coding gene Chr6:85733523-85752705 (+)
BALB/cJ MGP_BALBcJ_G0030934
protein coding gene Chr6:83312814-83329775 (+)
C3H/HeJ MGP_C3HHeJ_G0030776
protein coding gene Chr6:98695232-98712193 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031394
protein coding gene Chr6:89002608-89019569 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028579
protein coding gene Chr6:81593825-81609605 (+)
CAST/EiJ MGP_CASTEiJ_G0030043
protein coding gene Chr6:85748302-85765263 (+)
CBA/J MGP_CBAJ_G0030621
protein coding gene Chr6:92491712-92508673 (+)
DBA/2J MGP_DBA2J_G0030774
protein coding gene Chr6:82603379-82620340 (+)
FVB/NJ MGP_FVBNJ_G0030727
protein coding gene Chr6:81805519-81822479 (+)
LP/J MGP_LPJ_G0030853
protein coding gene Chr6:86613912-86630873 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030763
protein coding gene Chr6:96696385-96713345 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031418
protein coding gene Chr6:85534232-85552464 (+)
PWK/PhJ MGP_PWKPhJ_G0029758
protein coding gene Chr6:81538620-81555610 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029586
protein coding gene Chr6:84392309-84409242 (+)
WSB/EiJ MGP_WSBEiJ_G0030124
protein coding gene Chr6:85983006-86001903 (+)



Homology
more
  • Human Ortholog
    CCT7, chaperonin containing TCP1 subunit 7
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CCT7, chaperonin containing TCP1 subunit 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCTETA, CCTH, NIP7-1, TCP1ETA
  • Links
    NCBI Gene ID: 10574
    neXtProt AC: NX_Q99832
    UniProt: Q99832

  • Chr Location
    2p13.2; chr2:73233431-73253022 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 4694
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CCT7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030007 Ensembl Gene Model | MGI Sequence Detail 16962 C57BL/6J ±  kb
transcript ENSMUST00000032078 Ensembl | MGI Sequence Detail 2441 Not Applicable  
polypeptide ENSMUSP00000032078 Ensembl | MGI Sequence Detail 544 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    11 Sequences
  • Protein Ontology
    PR:000005156 T-complex protein 1 subunit eta
  • InterPro Domains
    IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
    IPR002423 Chaperonin Cpn60/TCP-1 family
    IPR002194 Chaperonin TCP-1, conserved site
    IPR027409 GroEL-like apical domain superfamily
    IPR027413 GroEL-like equatorial domain superfamily
    IPR012720 T-complex protein 1, eta subunit
    IPR027410 TCP-1-like chaperonin intermediate domain superfamily
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-35645, MGI:2141360, MGI:2141529
References
more
  • Summaries
    All 45
    Gene Ontology 11
    Phenotypes 9
  • Earliest
    J:18119 O'Bryan JP, et al., axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. Mol Cell Biol. 1991 Oct;11(10):5016-31
  • Latest
    J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory