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Cct7 Gene Detail
Summary
  • Symbol
    Cct7
  • Name
    chaperonin containing Tcp1, subunit 7 (eta)
  • Synonyms
    Ccth, Cctz
  • Feature Type
    protein coding gene
  • IDs
    MGI:107184
    NCBI Gene: 12468
  • Gene Overview
    MyGene.info: CCT7
Location & Maps
more
  • Sequence Map
    Chr6:85451514-85468475 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16962 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.46 cM, cytoband D1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CCT7, chaperonin containing TCP1 subunit 7
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CCT7, chaperonin containing TCP1 subunit 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CCTETA, CCTH, NIP7-1, TCP1ETA
  • Links
    NCBI Gene ID: 10574
    neXtProt AC: NX_Q99832

  • Chr Location
    2p13.2; chr2:73233425-73253022 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4694
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CCT7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    28
  • Gene trapped
    25
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Cct7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057881 VEGA Gene Model | MGI Sequence Detail 16962 C57BL/6J ±  kb
transcript OTTMUST00000142125 VEGA | MGI Sequence Detail 2441 Not Applicable  
polypeptide OTTMUSP00000074191 VEGA | MGI Sequence Detail 544 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    24 from dbSNP Build 142
Protein
Information
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  • UniProt
    11 Sequences
  • Protein Ontology
    PR:000005156 T-complex protein 1 subunit eta
  • InterPro Domains
    IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
    IPR002423 Chaperonin Cpn60/TCP-1 family
    IPR002194 Chaperonin TCP-1, conserved site
    IPR027409 GroEL-like apical domain
    IPR027413 GroEL-like equatorial domain
    IPR012720 T-complex protein 1, eta subunit
    IPR027410 TCP-1-like chaperonin intermediate domain
Molecular
Reagents
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  • All nucleic 20
    cDNA 20

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-35645, MGI:2141360, MGI:2141529
References
more
  • Summaries
    All 40
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:25228 Kubota H, et al., Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. Curr Biol. 1994 Feb 1;4(2):89-99
  • Latest
    J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory