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Elf1 Gene Detail
Summary
  • Symbol
    Elf1
  • Name
    E74-like factor 1
  • Synonyms
    Elf-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:107180
    NCBI Gene: 13709
  • Gene Overview
    MyGene.info: ELF1
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr14:79481194-79582491 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      101298 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 42.67 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ELF1, E74 like ETS transcription factor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ELF1, E74 like ETS transcription factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EFTUD1, RIA1
  • Links
    NCBI Gene ID: 1997
    neXtProt AC: NX_P32519
    UniProt: P32519

  • Chr Location
    13q14.11; chr13:40931919-41061414 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7303
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ELF1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene show no obvious phenotypic abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 13709 NCBI Gene Model | MGI Sequence Detail 101298 C57BL/6J ±  kb
transcript NM_007920 RefSeq | MGI Sequence Detail 4232 C57BL/6  
polypeptide Q60775 UniProt | EBI | MGI Sequence Detail 612 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    249 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 15
    Primer pair 3

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-35641
References
more
  • Summaries
    All 65
    Developmental Gene Expression 13
    Gene Ontology 8
    Phenotypes 13
  • Earliest
    J:21040 Gunther CV, et al., Identification of ETS domain proteins in murine T lymphocytes that interact with the Moloney murine leukemia virus enhancer. Mol Cell Biol. 1994 Nov;14(11):7569-80
  • Latest
    J:251264 Kumazoe M, et al., Green Tea Polyphenol EGCG Upregulates Tollip Expression by Suppressing Elf-1 Expression. J Immunol. 2017 Nov 1;199(9):3261-3269

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/03/2018
MGI 6.11
The Jackson Laboratory