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Tfdp2 Gene Detail
Summary
  • Symbol
    Tfdp2
  • Name
    transcription factor Dp 2
  • Synonyms
    1110029I05Rik, A330080J22Rik, DP-3, DP3, DP3
  • Feature Type
    protein coding gene
  • IDs
    MGI:107167
    NCBI Gene: 211586
  • Alliance
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:96078348-96205699 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 50.31 cM, cytoband E4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3479 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107167
protein coding gene Chr9:96078328-96205699 (+)
129S1/SvImJ ENSMUSG00200015968
protein coding gene Chr9:93221314-93320973 (+)
A/J ENSMUSG00195017584
protein coding gene Chr9:92488831-92588511 (+)
AKR/J ENSMUSG00220036634
protein coding gene Chr9:92840801-92941605 (+)
BALB/cJ ENSMUSG00180019299
protein coding gene Chr9:92808414-92908102 (+)
C3H/HeJ ENSMUSG00175011226
protein coding gene Chr9:93148418-93248089 (+)
C57BL/6NJ ENSMUSG00215016879
protein coding gene Chr9:93121231-93221791 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032537
protein coding gene Chr9:91795584-91916567 (+)
CAST/EiJ ENSTCUG00005012828
protein coding gene Chr9:92972017-93074612 (+)
CBA/J ENSMUSG00210015150
protein coding gene Chr9:92990417-93090099 (+)
DBA/2J ENSMUSG00185011708
protein coding gene Chr9:93176507-93276203 (+)
FVB/NJ ENSMUSG00205015497
protein coding gene Chr9:93181314-93281015 (+)
JF1/MsJ ENSUMUG00000039668
protein coding gene Chr9:92875749-92978786 (+)
LP/J ENSMUSG00230019267
protein coding gene Chr9:93344857-93444536 (+)
NOD/ShiLtJ ENSMUSG00190028600
protein coding gene Chr9:92807830-92908397 (+)
NZO/HlLtJ ENSMUSG00225019641
protein coding gene Chr9:93425887-93554921 (+)
PWK/PhJ ENSLUMG00010026173
protein coding gene Chr9:92873046-92976146 (+)
SPRET/EiJ ENSMSPG00010003652
protein coding gene Chr9:94664845-94785092 (+)
WSB/EiJ ENSIUOG00005021137
protein coding gene Chr9:92249761-92349482 (+)



Homology
more
  • Human Ortholog
    TFDP2, transcription factor Dp-2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TFDP2, transcription factor Dp-2
  • Synonyms
    DP2
  • Links
    NCBI Gene ID: 7029
    UniProt: Q14188

  • Chr Location
    3q23; chr3:141944428-142149544 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 211586 NCBI Gene Model | MGI Sequence Detail 127352 C57BL/6J ±  kb
transcript NM_001408522 RefSeq | MGI Sequence Detail 7538 C57BL/6  
polypeptide Q64163 UniProt | EBI | MGI Sequence Detail 446 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    18 Sequences
  • Protein Ontology
    PR:000016270 transcription factor Dp-2
  • InterPro Domains
    IPR003316 E2F/DP family, winged-helix DNA-binding domain
    IPR037241 E2F-DP heterodimerization region
    IPR015648 Transcription factor DP
    IPR014889 Transcription factor DP, C-terminal
    IPR038168 Transcription factor DP, C-terminal domain superfamily
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
less
  • All nucleic 30
    cDNA 29
    Primer pair 1
    Antibodies 2

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-35628, MGI:2442132, MGI:2442257
References
more
  • Summaries
    All 67
    Developmental Gene Expression 12
    Gene Ontology 8
    Phenotypes 19
  • Earliest
    J:25966 Zhang Y, et al., Cloning and characterization of human DP2, a novel dimerization partner of E2F. Oncogene. 1995 Jun 1;10(11):2085-93
  • Latest
    J:361732 Rousseau V, et al., Trim33 masks a non-transcriptional function of E2f4 in replication fork progression. Nat Commun. 2023 Aug 23;14(1):5143

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory