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Tfdp2 Gene Detail
Summary
  • Symbol
    Tfdp2
  • Name
    transcription factor Dp 2
  • Synonyms
    1110029I05Rik, A330080J22Rik, DP3, DP3, DP-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:107167
    NCBI Gene: 211586
  • Gene Overview
    MyGene.info: TFDP2
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:96196275-96323646 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 50.31 cM, cytoband E4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1327 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107167
protein coding gene Chr9:96196245-96323646 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035142
protein coding gene Chr9:97369348-97501924 (+)
A/J MGP_AJ_G0035123
protein coding gene Chr9:93976201-94099898 (+)
AKR/J MGP_AKRJ_G0035055
protein coding gene Chr9:96260989-96397132 (+)
BALB/cJ MGP_BALBcJ_G0035116
protein coding gene Chr9:93666513-93788023 (+)
C3H/HeJ MGP_C3HHeJ_G0034826
protein coding gene Chr9:96683518-96805497 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035636
protein coding gene Chr9:100163797-100296423 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032537
protein coding gene Chr9:91795584-91916567 (+)
CAST/EiJ MGP_CASTEiJ_G0034138
protein coding gene Chr9:96432937-96571032 (+)
CBA/J MGP_CBAJ_G0034794
protein coding gene Chr9:103639109-103783366 (+)
DBA/2J MGP_DBA2J_G0034956
protein coding gene Chr9:93503659-93625502 (+)
FVB/NJ MGP_FVBNJ_G0034904
protein coding gene Chr9:92351168-92474492 (+)
LP/J MGP_LPJ_G0035035
protein coding gene Chr9:97642173-97768488 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034943
protein coding gene Chr9:105629780-105775689 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035658
protein coding gene Chr9:96487497-96626959 (+)
PWK/PhJ MGP_PWKPhJ_G0033845
protein coding gene Chr9:93660829-93793731 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033680
protein coding gene Chr9:96543188-96675203 (+)
WSB/EiJ MGP_WSBEiJ_G0034258
protein coding gene Chr9:96361458-96491792 (+)



Homology
more
  • Human Ortholog
    TFDP2, transcription factor Dp-2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TFDP2, transcription factor Dp-2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DP2
  • Links
    NCBI Gene ID: 7029
    neXtProt AC: NX_Q14188
    UniProt: Q14188

  • Chr Location
    3q23; chr3:141944428-142149544 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032411 Ensembl Gene Model | MGI Sequence Detail 127372 C57BL/6J ±  kb
transcript ENSMUST00000188750 Ensembl | MGI Sequence Detail 1713 Not Applicable  
polypeptide ENSMUSP00000139926 Ensembl | MGI Sequence Detail 446 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    17 Sequences
  • InterPro Domains
    IPR003316 E2F/DP family, winged-helix DNA-binding domain
    IPR037241 E2F-DP heterodimerization region
    IPR015648 Transcription factor DP
    IPR028314 Transcription factor DP2
    IPR014889 Transcription factor DP, C-terminal
    IPR038168 Transcription factor DP, C-terminal domain superfamily
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
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  • All nucleic 28
    cDNA 27
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-35628, MGI:2442132, MGI:2442257
References
more
  • Summaries
    All 54
    Developmental Gene Expression 11
    Gene Ontology 7
    Phenotypes 15
  • Earliest
    J:29532 Ormondroyd E, et al., A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F. Oncogene. 1995 Oct 19;11(8):1437-46
  • Latest
    J:215696 Chen C, et al., Global analysis of induced transcription factors and cofactors identifies Tfdp2 as an essential coregulator during terminal erythropoiesis. Exp Hematol. 2014 Jun;42(6):464-76.e5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory