About   Help   FAQ
Srpk1
Gene Detail
Symbol

Name
ID
Srpk1
serine/arginine-rich protein specific kinase 1
MGI:106908
Synonyms
SR protein-specific kinase 1
Feature Type
protein coding gene
Genetic Map
Chromosome 17
14.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr17:28587648-28622521 bp, - strand
From VEGA annotation of GRCm38

  34874 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110962  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: serine/threonine-protein kinase
Gene Tree: Srpk1

Human
homologs
Human Homolog SRPK1, SRSF protein kinase 1
NCBI Gene ID 6732
neXtProt AC  NX_Q96SB4
Human Synonyms  SFRSK1
Human Chr (Location)  6p21.31; chr6:35833034-35921180 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(62) : Gene trapped(62)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Srpk1 interacts with 326 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (33 annotations)
Process cell differentiation, chromosome segregation, ...
Component cytoplasm, endoplasmic reticulum, ...
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (95)    Tissues (95)    Images (16)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 95
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(20) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000024247 (Evidence)
Ensembl Gene ModelENSMUSG00000004865 (Evidence)
Entrez Gene20815 (Evidence)
DFCITC1575142, TC1607410, TC1756936, TC1682268
DoTSDT.487812, DT.94274873, DT.40149061, DT.101718684, DT.101403424
NIA Mouse Gene IndexU037611
EC2.7.11.1
Consensus CDS ProjectCCDS37531.1
International Mouse Knockout Project StatusSrpk1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024247 VEGA Gene Model | MGI Sequence Detail 34874 C57BL/6J ±  kb
transcript OTTMUST00000059342 VEGA | MGI Sequence Detail 4465 Not Applicable 
polypeptide OTTMUSP00000028859 VEGA | MGI Sequence Detail 648 Not Applicable 

For the selected sequences
All sequences(77) RefSeq(10) UniProt(15)
Polymorphisms
RFLP(1) : SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000015629 SRSF protein kinase 1
References
(Earliest) J:33905 Gul JF, et al., A serine kinase regulates intracellular localization of splicing factors in the cell cycle. Nature. 1994;369(6482):678-682
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(42)
Other
accession IDs
MGD-MRK-35369, MGI:2146973

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory