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Selplg
Gene Detail
 Symbol
Name
ID
Selplg
selectin, platelet (p-selectin) ligand
MGI:106689
Synonyms CD162, Psgl1, Psgl-1
Feature Type protein coding gene
Genetic Map
Chromosome 5
55.59 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr5:113817798-113830501 bp, - strand
From NCBI annotation of GRCm38

  12704 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2261  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Selplg

Human
homologs
Human Homolog SELPLG, selectin P ligand
NCBI Gene ID 6404
neXtProt AC  NX_Q14242
Human Synonyms  CD162, CLA, PSGL1, PSGL-1
Human Chr (Location)  12q24; chr12:108621895-108633959 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit neutrophillia and impaired leukocyte adhesion and rolling.
 
Interactions
Selplg interacts with 133 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell adhesion, leukocyte adhesive activation, ...
Component integral component of membrane, membrane, ...
Function carbohydrate binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (5)    Tissues (1)    Images (5)
Theiler Stages: 23
Assay TypeResults
RNA in situ 5
cDNA source data(38)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(39) Genomic(1) cDNA(38)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000048163 (Evidence)
Entrez Gene20345 (Evidence)
UniGene332590
DFCITC1572763, TC1587911, TC1710127
DoTSDT.101408875, DT.110695196, DT.40145623, DT.99864705
NIA Mouse Gene IndexU026593, U375907
PDB2EMT
Consensus CDS ProjectCCDS51621.1
International Mouse Knockout Project StatusSelplg
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 20345 NCBI Gene Model | MGI Sequence Detail 12704 C57BL/6J ±  kb
transcript NM_009151 RefSeq | MGI Sequence Detail 2604 C57BL/6 
polypeptide Q62170 UniProt | EBI | MGI Sequence Detail 397 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(4) UniProt(5)
Polymorphisms RFLP(1) : SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026195 P-selectin glycoprotein ligand 1
Protein Ontology PR:000001830 P-selectin glycoprotein ligand 1
Graphical View of Protein Domain Structure
References (Earliest) J:33106 Yang J, et al., Mouse P-selectin glycoprotein ligand-1: molecular cloning, chromosomal localization, and expression of a functional P-selectin receptor. Blood. 1996 May 15;87(10):4176-86
(Latest) J:208688 Krause DS, et al., Selectins and their ligands are required for homing and engraftment of BCR-ABL1+ leukemic stem cells in the bone marrow niche. Blood. 2014 Feb 27;123(9):1361-71
All references(102)
Other
accession IDs
MGD-MRK-35148

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory