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Sprr1a Gene Detail
Summary
  • Symbol
    Sprr1a
  • Name
    small proline-rich protein 1A
  • Feature Type
    protein coding gene
  • IDs
    MGI:106660
    NCBI Gene: 20753
  • Gene Overview
    MyGene.info: SPRR1A
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92483954-92485881 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106660
protein coding gene Chr3:92483952-92485895 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027499
protein coding gene Chr3:92934489-92936432 (-)
A/J MGP_AJ_G0027466
protein coding gene Chr3:90008812-90010755 (-)
AKR/J MGP_AKRJ_G0027431
protein coding gene Chr3:92115474-92117417 (-)
BALB/cJ MGP_BALBcJ_G0027474
protein coding gene Chr3:89820929-89822872 (-)
C3H/HeJ MGP_C3HHeJ_G0027214
protein coding gene Chr3:92343503-92345446 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027918
protein coding gene Chr3:96471671-96473614 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025267
protein coding gene Chr3:86652796-86654739 (-)
CAST/EiJ MGP_CASTEiJ_G0026661
protein coding gene Chr3:91755815-91757758 (-)
CBA/J MGP_CBAJ_G0027188
protein coding gene Chr3:99782903-99784846 (-)
DBA/2J MGP_DBA2J_G0027326
protein coding gene Chr3:89333177-89335120 (-)
FVB/NJ MGP_FVBNJ_G0027294
protein coding gene Chr3:87501312-87503255 (-)
LP/J MGP_LPJ_G0027434
protein coding gene Chr3:94148955-94150898 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027318
protein coding gene Chr3:106030298-106032241 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027977
protein coding gene Chr3:91848337-91850280 (-)
PWK/PhJ MGP_PWKPhJ_G0026394
protein coding gene Chr3:89221103-89223047 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026213
protein coding gene Chr3:90187409-90189352 (-)
WSB/EiJ MGP_WSBEiJ_G0026744
protein coding gene Chr3:92239938-92241881 (-)



Homology
more
  • Human Ortholog
    SPRR1A, small proline rich protein 1A
  • Vertebrate Orthologs
    3
  • Human Ortholog
    SPRR1A, small proline rich protein 1A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SPRK
  • Links
    NCBI Gene ID: 6698
    neXtProt AC: NX_P35321
    UniProt: P35321

  • Chr Location
    1q21.3; chr1:152984088-152985814 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20753 NCBI Gene Model | MGI Sequence Detail 1928 C57BL/6J ±  kb
transcript NM_009264 RefSeq | MGI Sequence Detail 807 C57BL/6  
polypeptide Q62266 UniProt | EBI | MGI Sequence Detail 144 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR026075 Small proline-rich protein/late cornified envelope protein
Molecular
Reagents
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  • All nucleic 29
    cDNA 26
    Primer pair 2
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-35118, MGI:2139753
References
more
  • Summaries
    All 44
    Developmental Gene Expression 13
    Diseases 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:32027 Kartasova T, et al., Sequence and expression patterns of mouse SPR1: Correlation of expression with epithelial function. J Invest Dermatol. 1996 Feb;106(2):294-304
  • Latest
    J:243411 Rutledge EA, et al., Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory