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Nap1l2 Gene Detail
Summary
  • Symbol
    Nap1l2
  • Name
    nucleosome assembly protein 1-like 2
  • Synonyms
    Bpx
  • Feature Type
    protein coding gene
  • IDs
    MGI:106654
    NCBI Gene: 17954
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:103184176-103186640 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 45.97 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    8 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106654
protein coding gene ChrX:103184059-103186664 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035981
protein coding gene ChrX:99791402-99793866 (-)
A/J MGP_AJ_G0035962
protein coding gene ChrX:99736220-99738684 (-)
AKR/J MGP_AKRJ_G0035880
protein coding gene ChrX:102751038-102753502 (-)
BALB/cJ MGP_BALBcJ_G0035951
protein coding gene ChrX:98538648-98541112 (-)
C3H/HeJ MGP_C3HHeJ_G0035657
protein coding gene ChrX:100266686-100269150 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036478
protein coding gene ChrX:102740236-102742700 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033306
protein coding gene ChrX:97396785-97399254 (-)
CAST/EiJ MGP_CASTEiJ_G0034944
protein coding gene ChrX:84535784-84538248 (-)
CBA/J MGP_CBAJ_G0035633
protein coding gene ChrX:105939946-105942410 (-)
DBA/2J MGP_DBA2J_G0035787
protein coding gene ChrX:98985394-98987858 (-)
FVB/NJ MGP_FVBNJ_G0035727
protein coding gene ChrX:98308680-98311144 (-)
LP/J MGP_LPJ_G0035879
protein coding gene ChrX:100824433-100826897 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035760
protein coding gene ChrX:110570371-110572835 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036504
protein coding gene ChrX:99492484-99494948 (-)
PWK/PhJ MGP_PWKPhJ_G0034642
protein coding gene ChrX:82128919-82131383 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034470
protein coding gene ChrX:85226852-85229319 (-)
WSB/EiJ MGP_WSBEiJ_G0035084
protein coding gene ChrX:98228314-98230778 (-)



Homology
more
  • Human Ortholog
    NAP1L2, nucleosome assembly protein 1 like 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    NAP1L2, nucleosome assembly protein 1 like 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BPX
  • Links
    NCBI Gene ID: 4674
    neXtProt AC: NX_Q9ULW6
    UniProt: Q9ULW6

  • Chr Location
    Xq13.2; chrX:73212299-73214874 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    4 phenotype references
Chimeric embryos with high contribution from heterozygous or homozygous null mutant ES cells exhibit severely abnormal neural tube development and die by embryonic day 14 (E14).
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000082229 Ensembl Gene Model | MGI Sequence Detail 2465 C57BL/6J ±  kb
transcript ENSMUST00000121720 Ensembl | MGI Sequence Detail 2465 Not Applicable  
polypeptide ENSMUSP00000112677 Ensembl | MGI Sequence Detail 460 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 5
    cDNA 15

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-32160, MGD-MRK-35112
References
more
  • Summaries
    All 29
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:30901 Rougeulle C, et al., Cloning and characterization of a murine brain specific gene Bpx and its human homologue lying within the Xic candidate region. Hum Mol Genet. 1996 Jan;5(1):41-9
  • Latest
    J:240582 Carmona-Mora P, et al., The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation. Hum Genet. 2015 Oct;134(10):1099-115

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory