Slc30a2 MGI Mouse Gene Detail - MGI:106637 - solute carrier family 30 (zinc transporter), member 2

Slc30a2 Gene Detail

Symbol

Slc30a2
Name

solute carrier family 30 (zinc transporter), member 2
Synonyms

Znt2

Feature Type

protein coding gene
IDs

MGI:106637
NCBI Gene: 230810

Sequence Map

Chr4:134343181-134354484 bp, + strand
From VEGA annotation of GRCm38

Mouse Genome Browser
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Sequence

11304 bp ± kb flank
Genome Browsers

VEGA | Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 66.61 cM
Mapping Data

3 experiments

Human Ortholog

SLC30A2, solute carrier family 30 member 2

Vertebrate Orthologs

10

Human Ortholog

SLC30A2, solute carrier family 30 member 2
Orthology source: HomoloGene, HGNC
Synonyms

PP12488, TNZD, ZnT-2, ZNT2
Links

HGNC:11013

NCBI Gene ID: 7780

neXtProt AC: NX_Q9BRI3
Chr Location

1p35.3; chr1:26038022-26046138 (-) GRCh38.p2

HomoloGene

Vertebrate Homology Class 40855
1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
HCOP

human homology predictions: SLC30A2
Protein SuperFamily

cation efflux protein
Gene Tree

Slc30a2

Diseases

1 with human SLC30A2 associations

				Human Disease	Mouse Models
				Zinc Deficiency, Transient Neonatal; TNZD OMIM: 608118

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

7 phenotype references

All Mutations and Alleles

14
Chemically induced (other)

2
Gene trapped

10
Radiation induced

1
Targeted

1
Genomic Mutations

4 involving Slc30a2
Incidental Mutations

APF

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All GO Annotations

21
GO References

5

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	receptor	receptor binding	RNA binding	transcription	transferase	transporter

Biological Process

nucleic acid-templated transcription	carbohydrate derivative metabolism	cell death	cell differentiation	cell proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

21
Tissues

3
cDNA Data

26
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO
Other Vertebrate Links

Xenbase slc30a2

ZFIN slc30a2

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Slc30a2 interacts with 193 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

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All Sequences

32
RefSeq

4
UniProt

4
CCDS

CCDS38915.1
UniGene

358876

			Length	Strain/Species	Flank
genomic	OTTMUSG00000010829	VEGA Gene Model \| MGI Sequence Detail	11304	C57BL/6J	± kb
transcript	OTTMUST00000025324	VEGA \| MGI Sequence Detail	3153	Not Applicable
polypeptide	OTTMUSP00000011613	VEGA \| MGI Sequence Detail	371	Not Applicable

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SNPs within 2kb

177 from dbSNP Build 142

RFLP

1

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UniProt

4 Sequences
Protein Ontology

PR:000015075 zinc transporter 2
InterPro Domains

IPR002524 Cation efflux protein

IPR027469 Cation efflux protein transmembrane domain

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All nucleic 30

Genomic 1

cDNA 27

Primer pair 1

Other 1

Microarray probesets 1

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MGD-MRK-35094

Summaries

All 29

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 7
Earliest

J:32792 Palmiter RD, et al., ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration. EMBO J. 1996 Apr 15;15(8):1784-91
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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