Slc30a2
Gene Detail

Symbol

Name
ID

Slc30a2
solute carrier family 30 (zinc transporter), member 2
MGI:106637

Synonyms

Znt2

Feature Type

protein coding gene

Genetic Map

Chromosome 4
66.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr4:134343181-134354484 bp, + strand From VEGA annotation of GRCm38   11304 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:40855  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: cation efflux protein
Gene Tree: Slc30a2

Human
homologs

Human Homolog		SLC30A2, solute carrier family 30 (zinc transporter), member 2
NCBI Gene ID		7780
neXtProt AC		NX_Q9BRI3
Human Synonyms		PP12488, TNZD, ZnT-2, ZNT2
Human Chr (Location)		1p35.3; chr1:26038023-26046113 (-)  GRCh38
Disease Associations		(1) Diseases Associated with Human SLC30A2

Mutations,
alleles, and
phenotypes

All mutations/alleles(11) : Gene trapped(10) Targeted(1)
Genomic Mutations involving Slc30a2 (1)
Incidental mutations (data from APF )

Interactions

Slc30a2 interacts with 193 markers (Mir7-1, Mir7-2, Mir7b, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (18 annotations)

Process	cation transport, divalent inorganic cation transport, ...
Component	cytoplasm, cytoplasmic membrane-bounded vesicle, ...
Function	cation transmembrane transporter activity, zinc ion transmembrane transporter activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)

Data Summary: Results (21)    Tissues (3)    Images (17)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	21

cDNA source data(26)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(30) Genomic(1) cDNA(27) Primer pair(1) Other(1)
Microarray probesets(1)

Other database
links

VEGA Gene Model	OTTMUSG00000010829 (Evidence)
Ensembl Gene Model	ENSMUSG00000028836 (Evidence)
Entrez Gene	230810 (Evidence)
UniGene	358876
DFCI	TC1604066, TC1604033, TC1595307
DoTS	DT.97392132, DT.101190578, DT.55261707
NIA Mouse Gene Index	U004934
Consensus CDS Project	CCDS38915.1
International Mouse Knockout Project Status	Slc30a2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000010829	VEGA Gene Model | MGI Sequence Detail	11304	C57BL/6J
transcript	OTTMUST00000025324	VEGA | MGI Sequence Detail	3153	Not Applicable
polypeptide	OTTMUSP00000011613	VEGA | MGI Sequence Detail	371	Not Applicable

All sequences(45) RefSeq(7) UniProt(7)

Polymorphisms

RFLP(1) : SNPs within 2kb(171 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR002524	Cation efflux protein
InterPro	IPR027469	Cation efflux protein transmembrane domain
Protein Ontology	PR:000015075	zinc transporter 2

References

(Earliest) J:32792 Palmiter RD, et al., ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration. EMBO J. 1996 Apr 15;15(8):1784-91
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Other
accession IDs

MGD-MRK-35094