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Slc30a2 Gene Detail
Summary
  • Symbol
    Slc30a2
  • Name
    solute carrier family 30 (zinc transporter), member 2
  • Synonyms
    Znt2
  • Feature Type
    protein coding gene
  • IDs
    MGI:106637
    NCBI Gene: 230810
Location & Maps
more
  • Sequence Map
    Chr4:134343181-134354484 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11304 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 66.61 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SLC30A2, solute carrier family 30 member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC30A2, solute carrier family 30 member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PP12488, TNZD, ZnT-2, ZNT2
  • Links
    NCBI Gene ID: 7780
    neXtProt AC: NX_Q9BRI3

  • Chr Location
    1p35.3; chr1:26038022-26046138 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human SLC30A2 associations

Human Disease Mouse Models
       Zinc Deficiency, Transient Neonatal; TNZD   OMIM: 608118
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    2
  • Gene trapped
    10
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Slc30a2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010829 VEGA Gene Model | MGI Sequence Detail 11304 C57BL/6J ±  kb
transcript OTTMUST00000025324 VEGA | MGI Sequence Detail 3153 Not Applicable  
polypeptide OTTMUSP00000011613 VEGA | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    177 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000015075 zinc transporter 2
  • InterPro Domains
    IPR002524 Cation efflux protein
    IPR027469 Cation efflux protein transmembrane domain
Molecular
Reagents
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  • All nucleic 30
    Genomic 1
    cDNA 27
    Primer pair 1
    Other 1

    Microarray probesets 1
Other
Accession IDs
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MGD-MRK-35094
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:32792 Palmiter RD, et al., ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration. EMBO J. 1996 Apr 15;15(8):1784-91
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory