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Atp5me Gene Detail
Summary
  • Symbol
    Atp5me
  • Name
    ATP synthase membrane subunit e
  • Synonyms
    2610008D24Rik, Atp5k, Lfm1
  • Feature Type
    protein coding gene
  • IDs
    MGI:106636
    NCBI Gene: 11958
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:108581112-108582265 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 53.11 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    112 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    2
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106636
 protein coding gene Chr5:108581110-108582314 (-)
129S1/SvImJ ENSMUSG00200021842
 protein coding gene Chr5:102330680-102331884 (-)
A/J ENSMUSG00195034555
 protein coding gene Chr5:101787556-101788760 (-)
AKR/J ENSMUSG00220043984
 protein coding gene Chr5:101338050-101339254 (-)
BALB/cJ ENSMUSG00180043881
 protein coding gene Chr5:101940391-101941595 (-)
C3H/HeJ ENSMUSG00175039927
 protein coding gene Chr5:103990160-103991363 (-)
C57BL/6NJ ENSMUSG00215018980
 protein coding gene Chr5:101984066-101985270 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027519
 protein coding gene Chr5:101315663-101316877 (-)
CAST/EiJ ENSTCUG00005030381
 protein coding gene Chr5:101225383-101226585 (-)
CBA/J ENSMUSG00210036776
 protein coding gene Chr5:102747739-102748942 (-)
DBA/2J ENSMUSG00185044321
 protein coding gene Chr5:105643749-105644953 (-)
FVB/NJ ENSMUSG00205026741
 protein coding gene Chr5:101674367-101675570 (-)
JF1/MsJ ENSUMUG00000011756
 protein coding gene Chr5:108704473-108705676 (-)
LP/J ENSMUSG00230031115
 protein coding gene Chr5:109871727-109872931 (-)
NOD/ShiLtJ ENSMUSG00190022988
 protein coding gene Chr5:101639930-101641134 (-)
NZO/HlLtJ ENSMUSG00225025843
 protein coding gene Chr5:117493581-117494785 (-)
PWK/PhJ ENSLUMG00010014616
 protein coding gene Chr5:100690591-100691794 (-)
SPRET/EiJ ENSMSPG00010040505
 protein coding gene Chr5:103796038-103797231 (-)
WSB/EiJ ENSIUOG00005037059
 protein coding gene Chr5:104369578-104370782 (-)



Homology
more
  • Human Ortholog
    ATP5ME, ATP synthase membrane subunit e
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP5ME, ATP synthase membrane subunit e
  • Synonyms
    ATP5I, ATP5K
  • Links
    NCBI Gene ID: 521
    UniProt: P56385

  • Chr Location
    4p16.3; chr4:672423-674369 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    35
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    5
  • Gene trapped
    26
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Atp5me
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    3 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    97
  • cDNA Data
    169
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 11958 NCBI Gene Model | MGI Sequence Detail 1154 C57BL/6J ±  kb
transcript NM_007507 RefSeq | MGI Sequence Detail 338 C57BL/6  
polypeptide Q06185 UniProt | EBI | MGI Sequence Detail 71 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000004460 ATP synthase F(0) complex subunit e, mitochondrial
    (term hierarchy)
  • InterPro Domains
    IPR008386 ATP synthase, F0 complex, subunit E, mitochondrial
  • GlyGen
    Q06185 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 174
    Genomic 3
    cDNA 169
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11788, MGD-MRK-35093, MGI:1917284, MGI:7469645
References
more
  • Summaries
    All 56
    Developmental Gene Expression 4
    Gene Ontology 10
    Phenotypes 14
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:346630 Zhang X, et al., Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature. Commun Biol. 2024 Mar 23;7(1):363
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory