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Rnf112 Gene Detail
Summary
  • Symbol
    Rnf112
  • Name
    ring finger protein 112
  • Synonyms
    bfp, Zfp179
  • Feature Type
    protein coding gene
  • IDs
    MGI:106611
    NCBI Gene: 22671
Location & Maps
more
  • Sequence Map
    Chr11:61448442-61454131 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5690 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 37.96 cM, cytoband B1.3
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    RNF112, ring finger protein 112
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RNF112, ring finger protein 112
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BFP, ZNF179
  • Links
    NCBI Gene ID: 7732
    neXtProt AC: NX_Q9ULX5

  • Chr Location
    17p11.2; chr17:19410790-19417276 (+)  GRCh38.p2

Human Diseases
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  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Targeted
    6
  • Genomic Mutations
    3 involving Rnf112
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005832 VEGA Gene Model | MGI Sequence Detail 5690 C57BL/6J ±  kb
transcript OTTMUST00000012946 VEGA | MGI Sequence Detail 3161 Not Applicable  
polypeptide OTTMUSP00000006023 VEGA | MGI Sequence Detail 679 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    45 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000014068 RING finger protein 112
  • InterPro Domains
    IPR030386 GB1/RHD3-type guanine nucleotide-binding (G) domain
    IPR015894 Guanylate-binding protein, N-terminal
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR018957 Zinc finger, C3HC4 RING-type
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
Molecular
Reagents
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  • All nucleic 18
    Genomic 2
    cDNA 16

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-35068, MGI:2144319, MGI:2144714
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Diseases 2
    Gene Ontology 4
    Phenotypes 16
  • Earliest
    J:32838 Matsuda Y, et al., Chromosome mapping of human (ZNF179), mouse, and rat genes for brain finger protein (bfp), a member of the RING finger family. Genomics. 1996 Apr 15;33(2):325-7
  • Latest
    J:203098 Pao PC, et al., A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cells. Cell Death Differ. 2011 Nov;18(11):1791-804

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory