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Prm3 Gene Detail
Summary
  • Symbol
    Prm3
  • Name
    protamine 3
  • Synonyms
    PX, Pxg, Pxg
  • Feature Type
    protein coding gene
  • IDs
    MGI:106601
    NCBI Gene: 19120
Location & Maps
more
  • Sequence Map
    Chr16:10790505-10790914 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      410 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 5.84 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    PRM3, protamine 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    PRM3, protamine 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 58531

  • Chr Location
    16p13.3; chr16:11273199-11273595 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    2
  • Targeted
    2
Males that are null homozygous for this gene have reduced sperm motility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048601 VEGA Gene Model | MGI Sequence Detail 410 C57BL/6J ±  kb
transcript OTTMUST00000124505 VEGA | MGI Sequence Detail 410 Not Applicable  
polypeptide OTTMUSP00000067730 VEGA | MGI Sequence Detail 101 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    41 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    Genomic 2
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-35057, MGI:3039637
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:43871 Schluter G, et al., The rat Prm3 gene is an intronless member of the protamine gene cluster and is expressed in haploid male germ cells. Cytogenet Cell Genet. 1995;71(4):352-5
  • Latest
    J:198562 Cantu C, et al., The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development. 2013 Jun;140(11):2377-86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory