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Fam89b Gene Detail
Summary
  • Symbol
    Fam89b
  • Name
    family with sequence similarity 89, member B
  • Synonyms
    1110021A21Rik, Fam89b, Mtvr2
  • Feature Type
    protein coding gene
  • IDs
    MGI:106595
    NCBI Gene: 17826
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5778115-5779681 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.34 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    16 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106595
 protein coding gene Chr19:5778115-5779694 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024725
 protein coding gene Chr19:2713934-2715500 (-)
A/J MGP_AJ_G0024691
 protein coding gene Chr19:2568129-2569695 (-)
AKR/J MGP_AKRJ_G0024664
 protein coding gene Chr19:2636830-2638396 (-)
BALB/cJ MGP_BALBcJ_G0024691
 protein coding gene Chr19:2563246-2564812 (-)
C3H/HeJ MGP_C3HHeJ_G0024459
 protein coding gene Chr19:2651887-2653453 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025138
 protein coding gene Chr19:2784366-2785932 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022568
 protein coding gene Chr19:2477703-2479273 (-)
CAST/EiJ MGP_CASTEiJ_G0023932
 protein coding gene Chr19:2671682-2673247 (-)
CBA/J MGP_CBAJ_G0024431
 protein coding gene Chr19:2912212-2913778 (-)
DBA/2J MGP_DBA2J_G0024558
 protein coding gene Chr19:2563474-2565040 (-)
FVB/NJ MGP_FVBNJ_G0024524
 protein coding gene Chr19:2560543-2562109 (-)
LP/J MGP_LPJ_G0024644
 protein coding gene Chr19:2688959-2690525 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024554
 protein coding gene Chr19:2750140-2751706 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025186
 protein coding gene Chr19:2653886-2655452 (-)
PWK/PhJ MGP_PWKPhJ_G0023678
 protein coding gene Chr19:2587075-2588641 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023482
 protein coding gene Chr19:2639947-2641513 (-)
WSB/EiJ MGP_WSBEiJ_G0023994
 protein coding gene Chr19:2664965-2666531 (-)



Homology
more
  • Human Ortholog
    FAM89B, family with sequence similarity 89 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM89B, family with sequence similarity 89 member B
  • Synonyms
    LRAP25, MTVR, MTVR1
  • Links
    NCBI Gene ID: 23625
    neXtProt AC: NX_Q8N5H3
    UniProt: Q8N5H3

  • Chr Location
    11q13.1; chr11:65572349-65574198 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    48
  • cDNA Data
    74
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024939 Ensembl Gene Model | MGI Sequence Detail 1567 C57BL/6J ±  kb
transcript ENSMUST00000099955 Ensembl | MGI Sequence Detail 1197 Not Applicable  
polypeptide ENSMUSP00000097538 Ensembl | MGI Sequence Detail 189 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 75
    Primer pair 1
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-35051, MGI:1913409
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:42524 Stankewich MC, et al., A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14158-63
  • Latest
    J:344818 Cordero A, et al., Rank ectopic expression in the presence of Neu and MMTV oncogenes alters mammary epithelial cell populations and their tumorigenic potential. J Mammary Gland Biol Neoplasia. 2023 Feb 18;28(1):2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory