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Omg
Gene Detail
Symbol

Name
ID
Omg
oligodendrocyte myelin glycoprotein
MGI:106586
Feature Type
protein coding gene
Genetic Map
Chromosome 11
46.79 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:79500982-79504084 bp, - strand
From VEGA annotation of GRCm38

  3103 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36099  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: OMG
Gene Tree: Omg

Human
homologs
OMG, oligodendrocyte myelin glycoprotein
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4974
neXtProt AC: NX_P23515

Human Synonyms: OMGP

Human Chr (Location): 17q11.2; chr17:31294650-31297362 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Genomic Mutations involving Omg (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit improved recovery from spinal cord injuries when on a mixed 129S4/SvJae C57BL/6 background.
 
Interactions
Omg interacts with 184 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cell adhesion, central nervous system myelination, ...
Component anchored component of membrane, membrane, ...
Function identical protein binding, protein homodimerization activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (2)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 2
cDNA source data(10)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase omg    NEW 
Molecular
reagents
All nucleic(13) Genomic(2) cDNA(10) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000000194 (Evidence)
Ensembl Gene Model ENSMUSG00000049612 (Evidence)
Entrez Gene 18377 (Evidence)
UniGene 93335
DFCI TC1583333
DoTS DT.55184190
NIA Mouse Gene Index U033151
Consensus CDS Project CCDS25120.2
International Mouse Phenotyping Consortium Status Omg
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000194 VEGA Gene Model | MGI Sequence Detail 3103 C57BL/6J ±  kb
transcript OTTMUST00000000577 VEGA | MGI Sequence Detail 2228 Not Applicable 
polypeptide OTTMUSP00000000249 VEGA | MGI Sequence Detail 443 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(15 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001611 Leucine-rich repeat
InterPro IPR025875 Leucine rich repeat 4
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
InterPro IPR003591 Leucine-rich repeat, typical subtype
Protein Ontology PR:000011637 oligodendrocyte-myelin glycoprotein
References
(Earliest) J:8591 Lebar R, et al., The M2 autoantigen of central nervous system myelin, a glycoprotein present in oligodendrocyte membrane. Clin Exp Immunol. 1986 Nov;66(2):423-34
(Latest) J:207231 Nishino J, et al., A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Elife. 2013;2:e00924
All references(37)
Other
accession IDs
MGD-MRK-35042

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory