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Tmx4 Gene Detail
Summary
  • Symbol
    Tmx4
  • Name
    thioredoxin-related transmembrane protein 4
  • Synonyms
    2810417D04Rik, 4930500L08Rik, D2Bwg1356e, mKIAA1162, Txndc13
  • Feature Type
    protein coding gene
  • IDs
    MGI:106558
    NCBI Gene: 52837
  • Gene Overview
    MyGene.info: TMX4
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:134594501-134644121 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 65.66 cM, cytoband G1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    101 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106558
 protein coding gene Chr2:134594185-134644145 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026553
 protein coding gene Chr2:138294888-138342956 (-)
A/J MGP_AJ_G0026517
 protein coding gene Chr2:132640444-132685493 (-)
AKR/J MGP_AKRJ_G0026491
 protein coding gene Chr2:136483360-136530527 (-)
BALB/cJ MGP_BALBcJ_G0026529
 protein coding gene Chr2:133067163-133110547 (-)
C3H/HeJ MGP_C3HHeJ_G0026272
 protein coding gene Chr2:136939660-136990067 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026974
 protein coding gene Chr2:142481445-142538095 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024351
 protein coding gene Chr2:127277933-127318366 (-)
CAST/EiJ MGP_CASTEiJ_G0025733
 protein coding gene Chr2:137273172-137329733 (-)
CBA/J MGP_CBAJ_G0026252
 protein coding gene Chr2:147792754-147846223 (-)
DBA/2J MGP_DBA2J_G0026386
 protein coding gene Chr2:132025738-132080670 (-)
FVB/NJ MGP_FVBNJ_G0026350
 protein coding gene Chr2:130653422-130693371 (-)
LP/J MGP_LPJ_G0026490
 protein coding gene Chr2:138491913-138533557 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026370
 protein coding gene Chr2:151607408-151662035 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027029
 protein coding gene Chr2:136470152-136521376 (-)
PWK/PhJ MGP_PWKPhJ_G0025469
 protein coding gene Chr2:131627044-131671848 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025271
 protein coding gene Chr2:135610923-135646148 (-)
WSB/EiJ MGP_WSBEiJ_G0025807
 protein coding gene Chr2:137421079-137469444 (-)



Homology
more
  • Human Ortholog
    TMX4, thioredoxin related transmembrane protein 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMX4, thioredoxin related transmembrane protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DJ971N18.2, PDIA14, TXNDC13
  • Links
    NCBI Gene ID: 56255
    neXtProt AC: NX_Q9H1E5
    UniProt: Q9H1E5

  • Chr Location
    20p12.3; chr20:7977353-8019829 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 10901
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TMX4
  • Gene Tree
    Tmx4
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1
  • Tissues
    1
  • cDNA Data
    12
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52837 NCBI Gene Model | MGI Sequence Detail 49621 C57BL/6J ±  kb
transcript NM_029148 RefSeq | MGI Sequence Detail 5162 C57BL/6  
polypeptide Q8C0L0 UniProt | EBI | MGI Sequence Detail 335 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-34252, MGI:1919415, MGI:1922285, MGI:2139068, MGI:2139273
References
more
  • Summaries
    All 54
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 3
    Phenotypes 26
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:276404 Cheng LC, et al., Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells. Nucleus. 2019 Dec;10(1):126-143
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/03/2019
MGI 6.14 		The Jackson Laboratory