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Lppr4
Gene Detail
Symbol

Name
ID
Lppr4
lipid phosphate phosphatase-related protein type 4
MGI:106530
Synonyms
D3Bwg0562e, mKIAA0455
Feature Type
protein coding gene
Genetic Map
Chromosome 3
50.57 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:117319145-117360876 bp, - strand
From VEGA annotation of GRCm38

  41732 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8895  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: LPPR4
Gene Tree: Lppr4

Human
homologs
LPPR4, lipid phosphate phosphatase-related protein type 4
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 9890
neXtProt AC: NX_Q7Z2D5

Human Synonyms: LPR4, PHP1, PRG1, PRG-1

Human Chr (Location): 1p21.2; chr1:99262953-99309584 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit reduced body weight, seizures, hyperexcitability of evoked fEPSP, and premature lethality around 3 weeks of age.
 
Interactions
Lppr4 interacts with 371 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process axonogenesis, inner ear development, ...
Component external side of plasma membrane, integral component of membrane, ...
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (24)    Tissues (24)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
cDNA source data(22)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100489346    NEW 
Molecular
reagents
All nucleic(23) cDNA(22) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000023917 (Evidence)
Ensembl Gene Model ENSMUSG00000044667 (Evidence)
Entrez Gene 229791 (Evidence)
UniGene 140138
DFCI TC1602660, TC1579828
DoTS DT.91587981, DT.87068443
NIA Mouse Gene Index U024580
EC 3.1.3.4
Consensus CDS Project CCDS17795.1
International Mouse Phenotyping Consortium Status Lppr4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023917 VEGA Gene Model | MGI Sequence Detail 41732 C57BL/6J ±  kb
transcript OTTMUST00000058425 VEGA | MGI Sequence Detail 5690 Not Applicable 
polypeptide OTTMUSP00000028305 VEGA | MGI Sequence Detail 766 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(290 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
Protein Ontology PR:000009906 lipid phosphate phosphatase-related protein type 4
References
(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(35)
Other
accession IDs
MGD-MRK-34224

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory