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Pnrc2
Gene Detail
Symbol

Name
ID
Pnrc2
proline-rich nuclear receptor coactivator 2
MGI:106512
Synonyms
0610011E17Rik, D4Bwg0593e
Feature Type
protein coding gene
Genetic Map
Chromosome 4
68.01 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr4:135870918-135873850 bp, - strand
From VEGA annotation of GRCm38

  2933 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9821  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pnrc2

Human
homologs
Human Homolog PNRC2, proline-rich nuclear receptor coactivator 2
NCBI Gene ID 55629
neXtProt AC  NX_Q9NPJ4
Human Chr (Location)  1p36.11; chr1:23959811-23963462 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(24) : Gene trapped(21) Targeted(3)
 
Mice homozygous for a null allele exhibit decreased body weight, decreased percent body fat, resistance to diet-induced obesity, increased energy expenditure and increase heat production.
 
Phenotype Images(2)
Interactions
Pnrc2 interacts with 191 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (78)    Tissues (22)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 78
cDNA source data(185)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(186) cDNA(185) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000009795 (Evidence)
Ensembl Gene ModelENSMUSG00000028675 (Evidence)
Entrez Gene52830 (Evidence)
UniGene29159
DFCITC1572334, TC1641030
DoTSDT.101395023, DT.103563846, DT.494568, DT.94366062
NIA Mouse Gene IndexU025663
Consensus CDS ProjectCCDS18792.1
International Mouse Knockout Project StatusPnrc2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009795 VEGA Gene Model | MGI Sequence Detail 2933 C57BL/6J ±  kb
transcript OTTMUST00000022702 VEGA | MGI Sequence Detail 1919 Not Applicable 
polypeptide OTTMUSP00000010360 VEGA | MGI Sequence Detail 140 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(6) UniProt(5)
Polymorphisms
SNPs within 2kb(57 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026780 Proline-rich nuclear receptor coactivator 1/2
InterPro IPR026781 Proline-rich nuclear receptor coactivator 2
Protein Ontology PR:000012952 proline-rich nuclear receptor coactivator 2
References
(Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
All references(42)
Other
accession IDs
MGD-MRK-34206, MGI:1915049

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory