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Washc2 Gene Detail
Summary
  • Symbol
    Washc2
  • Name
    WASH complex subunit 2`
  • Synonyms
    C530005J20Rik, D6Wsu116e, Fam21
  • Feature Type
    protein coding gene
  • IDs
    MGI:106463
    NCBI Gene: 28006
  • Gene Overview
    MyGene.info: WASHC2C
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:116208027-116262671 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 53.76 cM, cytoband F1
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    335 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106463
protein coding gene Chr6:116208027-116262686 (.)
129S1/SvImJ MGP_129S1SvImJ_G0031163
protein coding gene Chr6:118865465-118924637 (+)
A/J MGP_AJ_G0031133
protein coding gene Chr6:114309603-114365153 (+)
AKR/J MGP_AKRJ_G0031063
protein coding gene Chr6:117361347-117420098 (+)
BALB/cJ MGP_BALBcJ_G0031143
protein coding gene Chr6:114117145-114170620 (+)
C3H/HeJ MGP_C3HHeJ_G0030565
protein coding gene Chr6:66865923-66928177 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031602
protein coding gene Chr6:121906022-121976008 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028766
protein coding gene Chr6:111311891-111366343 (+)
CAST/EiJ MGP_CASTEiJ_G0030250
protein coding gene Chr6:117756298-117807069 (+)
CBA/J MGP_CBAJ_G0030829
protein coding gene Chr6:126691693-126758968 (+)
DBA/2J MGP_DBA2J_G0030983
protein coding gene Chr6:113226221-113279981 (+)
FVB/NJ MGP_FVBNJ_G0030936
protein coding gene Chr6:112416436-112470642 (+)
LP/J MGP_LPJ_G0031062
protein coding gene Chr6:118876209-118934836 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030971
protein coding gene Chr6:130845277-130904137 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031630
protein coding gene Chr6:117395630-117462776 (+)
PWK/PhJ MGP_PWKPhJ_G0029966
protein coding gene Chr6:112243912-112298382 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029794
protein coding gene Chr6:116139520-116198411 (+)
WSB/EiJ MGP_WSBEiJ_G0030334
protein coding gene Chr6:117670561-117726417 (+)



Homology
more
  • Human Ortholog
    WASHC2A, WASH complex subunit 2A
  • Vertebrate Orthologs
    11
  • Human Ortholog
    WASHC2A, WASH complex subunit 2A
    Orthology source: HomoloGene
  • Synonyms
    bA56A21.1, bA98I6.1, FAM21A, FAM21B
  • Links
    NCBI Gene ID: 387680
    neXtProt AC: NX_Q641Q2
    UniProt: Q641Q2

  • Chr Location
    10q11.23; chr10:50067888-50133509 (+)  GRCh38.p7

  • Human Ortholog
    WASHC2C, WASH complex subunit 2C
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAM21A, FAM21C, VPEF
  • Links
    NCBI Gene ID: 253725
    neXtProt AC: NX_Q9Y4E1
    UniProt: Q9Y4E1

  • Chr Location
    10q11.22; chr10:45727170-45792964 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 28006 NCBI Gene Model | MGI Sequence Detail 54645 C57BL/6J ±  kb
transcript NM_026585 RefSeq | MGI Sequence Detail 4305 C57BL/6  
polypeptide Q6PGL7 UniProt | EBI | MGI Sequence Detail 1334 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 201
    cDNA 200
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-34157, MGI:1915404
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:261316 Perez-Garcia V, et al., Placentation defects are highly prevalent in embryonic lethal mouse mutants. Nature. 2018 Mar 22;555(7697):463-468

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory