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Itfg1 Gene Detail
Summary
  • Symbol
    Itfg1
  • Name
    integrin alpha FG-GAP repeat containing 1
  • Synonyms
    2310047C21Rik, D8Wsu49e
  • Feature Type
    protein coding gene
  • IDs
    MGI:106419
    NCBI Gene: 71927
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:85717578-85840921 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 41.61 cM, cytoband C4
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    502 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106419
protein coding gene Chr8:85717557-85840949 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033905
protein coding gene Chr8:86673564-86807000 (-)
A/J MGP_AJ_G0033888
protein coding gene Chr8:83259154-83384097 (-)
AKR/J MGP_AKRJ_G0033814
protein coding gene Chr8:85738154-85869470 (-)
BALB/cJ MGP_BALBcJ_G0033881
protein coding gene Chr8:83402157-83530742 (-)
C3H/HeJ MGP_C3HHeJ_G0033592
protein coding gene Chr8:86360098-86491042 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034402
protein coding gene Chr8:90011986-90145905 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031342
protein coding gene Chr8:77041641-77165515 (-)
CAST/EiJ MGP_CASTEiJ_G0032922
protein coding gene Chr8:85777727-85906437 (-)
CBA/J MGP_CBAJ_G0033567
protein coding gene Chr8:93063776-93215318 (-)
DBA/2J MGP_DBA2J_G0033720
protein coding gene Chr8:82895065-83023763 (-)
FVB/NJ MGP_FVBNJ_G0033668
protein coding gene Chr8:81843542-81969017 (-)
LP/J MGP_LPJ_G0033812
protein coding gene Chr8:86789815-86925580 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033711
protein coding gene Chr8:95587966-95726250 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034419
protein coding gene Chr8:85725043-85853322 (-)
PWK/PhJ MGP_PWKPhJ_G0032626
protein coding gene Chr8:82142961-82270563 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032461
protein coding gene Chr8:84509335-84651731 (-)
WSB/EiJ MGP_WSBEiJ_G0033034
protein coding gene Chr8:86151779-86282129 (-)



Homology
more
  • Human Ortholog
    ITFG1, integrin alpha FG-GAP repeat containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ITFG1, integrin alpha FG-GAP repeat containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    2310047C21Rik, CDA08, LNKN-1, TIP
  • Links
    NCBI Gene ID: 81533
    neXtProt AC: NX_Q8TB96
    UniProt: Q8TB96

  • Chr Location
    16q12.1; chr16:47154387-47461274 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 12423
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ITFG1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    32 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031703 Ensembl Gene Model | MGI Sequence Detail 123344 C57BL/6J ±  kb
transcript ENSMUST00000034140 Ensembl | MGI Sequence Detail 3306 Not Applicable  
polypeptide ENSMUSP00000034140 Ensembl | MGI Sequence Detail 610 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 124
    cDNA 123
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-34113, MGI:1919177, MGI:2142495
References
more
  • Summaries
    All 60
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 32
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
  • Latest
    J:266142 Grosjean F, et al., Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice. PLoS One. 2018;13(9):e0204366

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory