Tspyl4 MGI Mouse Gene Detail - MGI:106393

Symbol

Tspyl4
Name

TSPY-like 4
Synonyms

2610102M01Rik, B230210I21Rik

Feature Type

protein coding gene
IDs

MGI:106393
NCBI Gene: 72480
Alliance

genome feature page
Transcription Start Sites

4 TSS

Sequence Map

Chr10:34173438-34177316 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 18.85 cM, cytoband B1
Mapping Data

5 experiments

SNPs within 2kb

188 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_106393	protein coding gene	Chr10:34173417-34177316 (+)
129S1/SvImJ	ENSMUSG00200007742	protein coding gene	Chr10:31018367-31022245 (+)
A/J	ENSMUSG00195015086	protein coding gene	Chr10:31294482-31298360 (+)
AKR/J	ENSMUSG00220027337	protein coding gene	Chr10:30991740-30995618 (+)
BALB/cJ	ENSMUSG00180015400	protein coding gene	Chr10:31414497-31418375 (+)
C3H/HeJ	ENSMUSG00175011540	protein coding gene	Chr10:31169514-31173392 (+)
C57BL/6NJ	ENSMUSG00215007545	protein coding gene	Chr10:30959161-30963039 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015235	protein coding gene	Chr10:30114761-30118640 (+)
CAST/EiJ	ENSTCUG00005025889	protein coding gene	Chr10:31418635-31422510 (+)
CBA/J	ENSMUSG00210025152	protein coding gene	Chr10:31096854-31100732 (+)
DBA/2J	ENSMUSG00185006581	protein coding gene	Chr10:31249687-31253565 (+)
FVB/NJ	ENSMUSG00205011170	protein coding gene	Chr10:31230522-31234400 (+)
JF1/MsJ	ENSUMUG00000023665	protein coding gene	Chr10:31029250-31033131 (+)
LP/J	ENSMUSG00230014065	protein coding gene	Chr10:33015250-33019128 (+)
NOD/ShiLtJ	ENSMUSG00190026759	protein coding gene	Chr10:31362713-31366591 (+)
NZO/HlLtJ	ENSMUSG00225033252	protein coding gene	Chr10:37273635-37277513 (+)
PWK/PhJ	ENSLUMG00010007515	protein coding gene	Chr10:31041154-31045031 (+)
SPRET/EiJ	ENSMSPG00010019072	protein coding gene	Chr10:31988872-31992764 (+)
WSB/EiJ	ENSIUOG00005013963	protein coding gene	Chr10:30803379-30807257 (+)

Human Ortholog

TSPYL4, TSPY like 4

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TSPYL4, TSPY like 4
Synonyms

dJ486I3.2
Links

HGNC:21559

NCBI Gene ID: 23270

UniProt: Q9UJ04
Chr Location

6q22.1; chr6:116249964-116254075 (-) GRCh38

MGI Vertebrate Homology

Tspyl4 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: TSPYL4
Gene Tree

Tspyl4

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

5
Chemically induced (other)

1
Endonuclease-mediated

3
Radiation induced

1
Genomic Mutations

2 involving Tspyl4
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

18 strains or lines available

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All GO Annotations

6
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

691
Tissues

15
cDNA Data

84
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

47
RefSeq

2
UniProt

4
CCDS

CCDS23778.1

Ensembl

ENSMUSG00000039485 (Evidence)
NCBI Gene

72480

			Length	Strain/Species	Flank
genomic	ENSMUSG00000039485	Ensembl Gene Model \| MGI Sequence Detail	3879	C57BL/6J	± kb
transcript	ENSMUST00000047935	Ensembl \| MGI Sequence Detail	3879	Not Applicable
polypeptide	ENSMUSP00000036360	Ensembl \| MGI Sequence Detail	406	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000016763 testis-specific Y-encoded-like protein 4

(term hierarchy)
InterPro Domains

IPR037231 NAP-like superfamily

IPR002164 Nucleosome assembly protein

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All nucleic 85

cDNA 84

Primer pair 1

Microarray probesets 6

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MGD-MRK-34086, MGI:1919730, MGI:1926127

Summaries

All 40

Developmental Gene Expression 3

Gene Ontology 2

Phenotypes 11
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Tspyl4:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr92929	Chr10:34173428-34173509 (+)	31 bp
Tssr92930	Chr10:34173558-34173573 (+)	128 bp
Tssr92931	Chr10:34175060-34175064 (+)	1,624 bp
Tssr92932	Chr10:34176837-34176854 (+)	3,408 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24