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Rgs7bp Gene Detail
Summary
  • Symbol
    Rgs7bp
  • Name
    regulator of G-protein signalling 7 binding protein
  • Synonyms
    A930030I01Rik, D13Bwg1146e, R7bp
  • Feature Type
    protein coding gene
  • IDs
    MGI:106334
    NCBI Gene: 52882
Location & Maps
more
  • Sequence Map
    Chr13:104947153-105054930 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      107778 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 56.90 cM, cytoband D1
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    RGS7BP, regulator of G-protein signaling 7 binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RGS7BP, regulator of G-protein signaling 7 binding protein
    Orthology source: HomoloGene
  • Synonyms
    R7BP
  • Links
    NCBI Gene ID: 401190
    neXtProt AC: NX_Q6MZT1

  • Chr Location
    5q12.3; chr5:64505539-64614657 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 2 genetic backgrounds
    7 phenotype references
Mice homozygous for a null allele exhibit normal behavior and brain morphology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021719 Ensembl Gene Model | MGI Sequence Detail 107778 C57BL/6J ±  kb
transcript ENSMUST00000063551 Ensembl | MGI Sequence Detail 5828 Not Applicable  
polypeptide ENSMUSP00000066614 Ensembl | MGI Sequence Detail 257 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    521 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000013963 regulator of G-protein signaling 7-binding protein
  • InterPro Domains
    IPR026512 RGS7BP/RGS9BP family
Molecular
Reagents
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  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-34026, MGI:1924468, MGI:2145292
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:213237 Ostrovskaya O, et al., RGS7/Gbeta5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling. Elife. 2014;3:e02053

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory