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Med10 Gene Detail
Summary
  • Symbol
    Med10
  • Name
    mediator complex subunit 10
  • Synonyms
    D13Wsu50e
  • Feature Type
    protein coding gene
  • IDs
    MGI:106331
    NCBI Gene: 28077
Location & Maps
more
  • Sequence Map
    Chr13:69809882-69816094 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6213 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MED10, mediator complex subunit 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MED10, mediator complex subunit 10
    Orthology source: HomoloGene
  • Synonyms
    L6, NUT2, TRG20
  • Links
    NCBI Gene ID: 84246
    neXtProt AC: NX_Q9BTT4

  • Chr Location
    5p15.31; chr5:6371926-6378526 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 44533
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: MED10
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Genomic Mutations
    1 involving Med10
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021598 Ensembl Gene Model | MGI Sequence Detail 6213 C57BL/6J ±  kb
transcript ENSMUST00000022089 Ensembl | MGI Sequence Detail 862 Not Applicable  
polypeptide ENSMUSP00000022089 Ensembl | MGI Sequence Detail 135 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    111 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010280 mediator of RNA polymerase II transcription subunit 10
  • InterPro Domains
    IPR019145 Mediator complex, subunit Med10
Molecular
Reagents
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  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-34023, MGI:2145175, MGI:2145222, MGI:2145500
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory