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Larp4b Gene Detail
Summary
  • Symbol
    Larp4b
  • Name
    La ribonucleoprotein domain family, member 4B
  • Synonyms
    D13Wsu64e, Larp5
  • Feature Type
    protein coding gene
  • IDs
    MGI:106330
    NCBI Gene: 217980
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:9143917-9224487 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 3.66 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    495 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106330
protein coding gene Chr13:9143643-9224487 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020223
protein coding gene Chr13:5730268-5814317 (+)
A/J MGP_AJ_G0020179
protein coding gene Chr13:5717182-5797721 (+)
AKR/J MGP_AKRJ_G0020154
protein coding gene Chr13:5780699-5867511 (+)
BALB/cJ MGP_BALBcJ_G0020162
protein coding gene Chr13:5724333-5805865 (+)
C3H/HeJ MGP_C3HHeJ_G0019966
protein coding gene Chr13:5904992-5986722 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020609
protein coding gene Chr13:6088970-6170218 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018216
protein coding gene Chr13:5663370-5746740 (+)
CAST/EiJ MGP_CASTEiJ_G0019504
protein coding gene Chr13:5625711-5707600 (+)
CBA/J MGP_CBAJ_G0019933
protein coding gene Chr13:6216435-6302980 (+)
DBA/2J MGP_DBA2J_G0020050
protein coding gene Chr13:5546585-5627799 (+)
FVB/NJ MGP_FVBNJ_G0020035
protein coding gene Chr13:5400477-5483897 (+)
LP/J MGP_LPJ_G0020124
protein coding gene Chr13:5830968-5916393 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020071
protein coding gene Chr13:6558167-6643465 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020637
protein coding gene Chr13:5744938-5830364 (+)
PWK/PhJ MGP_PWKPhJ_G0019267
protein coding gene Chr13:5579924-5662678 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019074
protein coding gene Chr13:5733390-5817330 (+)
WSB/EiJ MGP_WSBEiJ_G0019564
protein coding gene Chr13:5647444-5729264 (+)



Homology
more
  • Human Ortholog
    LARP4B, La ribonucleoprotein 4B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LARP4B, La ribonucleoprotein 4B
  • Synonyms
    KIAA0217, LARP5
  • Links
    NCBI Gene ID: 23185
    neXtProt AC: NX_Q92615
    UniProt: Q92615

  • Chr Location
    10p15.3; chr10:806914-931900 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033499 Ensembl Gene Model | MGI Sequence Detail 80571 C57BL/6J ±  kb
    transcript ENSMUST00000188211 Ensembl | MGI Sequence Detail 5610 Not Applicable  
    polypeptide ENSMUSP00000140993 Ensembl | MGI Sequence Detail 741 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 19
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-34022, MGI:2145195
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
    • Latest
      J:181631 Gehman LT, et al., The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Genes Dev. 2012 Mar 1;26(5):445-60

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    06/15/2021
    MGI 6.17
    The Jackson Laboratory