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Mpped1 Gene Detail
Summary
  • Symbol
    Mpped1
  • Name
    metallophosphoesterase domain containing 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:106316
    NCBI Gene: 223726
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:83663668-83742695 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 39.44 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2264 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106316
 protein coding gene Chr15:83656256-83742695 (+)
129S1/SvImJ ENSMUSGG00200054968
 protein coding gene Chr15:80847490-80868177 (+)
129S1/SvImJ ENSMUSG00200053317
 protein coding gene Chr15:80803333-80803510 (+)
A/J ENSMUSG00195043972
 protein coding gene Chr15:80728226-80728403 (+)
A/J ENSMUSGG00195055512
 protein coding gene Chr15:80772335-80793026 (+)
AKR/J ENSMUSG00220046892
 protein coding gene Chr15:80771399-80771576 (+)
AKR/J ENSMUSGG00220054310
 protein coding gene Chr15:80819795-80840476 (+)
BALB/cJ ENSMUSGG00180055001
 protein coding gene Chr15:80649187-80669878 (+)
BALB/cJ ENSMUSG00180045889
 protein coding gene Chr15:80605088-80605265 (+)
C3H/HeJ ENSMUSG00175045813
 protein coding gene Chr15:80916007-80916184 (+)
C3H/HeJ ENSMUSGG00175055149
 protein coding gene Chr15:80960108-80980799 (+)
C57BL/6NJ ENSMUSG00215050253
 protein coding gene Chr15:80693990-80694167 (+)
C57BL/6NJ ENSMUSGG00215055810
 protein coding gene Chr15:80738085-80758773 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020105
 protein coding gene Chr15:77779770-77859228 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210048057
 protein coding gene Chr15:80690983-80691160 (+)
CBA/J ENSMUSGG00210055089
 protein coding gene Chr15:80735077-80755769 (+)
DBA/2J ENSMUSG00185047203
 protein coding gene Chr15:80727372-80727549 (+)
DBA/2J ENSMUSGG00185057951
 protein coding gene Chr15:80771478-80792169 (+)
FVB/NJ ENSMUSG00205042530
 protein coding gene Chr15:80472986-80473163 (+)
FVB/NJ ENSMUSGG00205054649
 protein coding gene Chr15:80517109-80537788 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230043574
 protein coding gene Chr15:84043633-84043810 (+)
LP/J ENSMUSGG00230055525
 protein coding gene Chr15:84087756-84108441 (+)
NOD/ShiLtJ ENSMUSG00190030242
 protein coding gene Chr15:80708096-80708273 (+)
NZO/HlLtJ ENSMUSG00225047616
 protein coding gene Chr15:84375381-84375558 (+)
NZO/HlLtJ ENSMUSGG00225055283
 protein coding gene Chr15:84419511-84440191 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010049272
 protein coding gene Chr15:82103766-82182798 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MPPED1, metallophosphoesterase domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MPPED1, metallophosphoesterase domain containing 1
  • Synonyms
    239AB, C22orf1, FAM1A
  • Links
    NCBI Gene ID: 758
    UniProt: O15442

  • Chr Location
    22q13.2; chr22:43411196-43507850 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    660
  • Tissues
    15
  • cDNA Data
    40
  • Literature Summary
    8
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041708 Ensembl Gene Model | MGI Sequence Detail 79028 C57BL/6J ±  kb
transcript ENSMUST00000109470 Ensembl | MGI Sequence Detail 3281 Not Applicable  
polypeptide ENSMUSP00000105096 Ensembl | MGI Sequence Detail 326 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 41
    cDNA 40
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-34008, MGI:2146215
References
more
  • Summaries
    All 57
    Developmental Gene Expression 8
    Diseases 1
    Gene Ontology 2
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory