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Tars Gene Detail
Summary
  • Symbol
    Tars
  • Name
    threonyl-tRNA synthetase
  • Synonyms
    D15Wsu59e, ThrRS
  • Feature Type
    protein coding gene
  • IDs
    MGI:106314
    NCBI Gene: 110960
  • Gene Overview
    MyGene.info: TARS
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:11383663-11399658 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 5.60 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    248 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106314
protein coding gene Chr15:11382301-11399665 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021731
protein coding gene Chr15:8569440-8585435 (-)
A/J MGP_AJ_G0021691
protein coding gene Chr15:8302704-8318611 (-)
AKR/J MGP_AKRJ_G0021669
protein coding gene Chr15:8514503-8530498 (-)
BALB/cJ MGP_BALBcJ_G0021698
protein coding gene Chr15:8211726-8227701 (-)
C3H/HeJ MGP_C3HHeJ_G0021474
protein coding gene Chr15:8470684-8486659 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022137
protein coding gene Chr15:8886132-8902127 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019674
protein coding gene Chr15:7773005-7788961 (-)
CAST/EiJ MGP_CASTEiJ_G0020990
protein coding gene Chr15:8546205-8562200 (-)
CBA/J MGP_CBAJ_G0021443
protein coding gene Chr15:9114371-9130364 (-)
DBA/2J MGP_DBA2J_G0021567
protein coding gene Chr15:8176358-8192353 (-)
FVB/NJ MGP_FVBNJ_G0021545
protein coding gene Chr15:8030573-8046785 (-)
LP/J MGP_LPJ_G0021635
protein coding gene Chr15:8482391-8498362 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021570
protein coding gene Chr15:9350136-9366109 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022160
protein coding gene Chr15:8510156-8527227 (-)
PWK/PhJ MGP_PWKPhJ_G0020733
protein coding gene Chr15:8351425-8368665 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020571
protein coding gene Chr15:8456132-8473822 (-)
WSB/EiJ MGP_WSBEiJ_G0021046
protein coding gene Chr15:8502465-8518460 (-)



Homology
more
  • Human Ortholog
    TARS, threonyl-tRNA synthetase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TARS, threonyl-tRNA synthetase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ThrRS
  • Links
    NCBI Gene ID: 6897
    neXtProt AC: NX_P26639
    UniProt: P26639

  • Chr Location
    5p13.3; chr5:33440696-33468091 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 110960 NCBI Gene Model | MGI Sequence Detail 15996 C57BL/6J ±  kb
transcript NM_033074 RefSeq | MGI Sequence Detail 2636 C57BL/6  
polypeptide Q9D0R2 UniProt | EBI | MGI Sequence Detail 722 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 191
    cDNA 190
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-34006
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:263618 Chen Y, et al., A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities. Nucleic Acids Res. 2018 Apr 20;46(7):3643-3656

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory