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Mybbp1a Gene Detail
Summary
  • Symbol
    Mybbp1a
  • Name
    MYB binding protein (P160) 1a
  • Synonyms
    p160MBP, p67MBP
  • Feature Type
    protein coding gene
  • IDs
    MGI:106181
    NCBI Gene: 18432
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:72332181-72342594 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 44.29 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    72 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106181
protein coding gene Chr11:72332153-72342596 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018640
protein coding gene Chr11:73064942-73075347 (+)
A/J MGP_AJ_G0018608
protein coding gene Chr11:70333324-70343730 (+)
AKR/J MGP_AKRJ_G0018577
protein coding gene Chr11:72485358-72495771 (+)
BALB/cJ MGP_BALBcJ_G0018580
protein coding gene Chr11:70636748-70647161 (+)
C3H/HeJ MGP_C3HHeJ_G0018393
protein coding gene Chr11:72444807-72455220 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019031
protein coding gene Chr11:75284604-75295017 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016674
protein coding gene Chr11:67166758-67177390 (+)
CAST/EiJ MGP_CASTEiJ_G0017948
protein coding gene Chr11:72805892-72818711 (+)
CBA/J MGP_CBAJ_G0018365
protein coding gene Chr11:78630622-78641035 (+)
DBA/2J MGP_DBA2J_G0018474
protein coding gene Chr11:69970594-69981005 (+)
FVB/NJ MGP_FVBNJ_G0018465
protein coding gene Chr11:69512614-69523027 (+)
LP/J MGP_LPJ_G0018545
protein coding gene Chr11:73577564-73587969 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018488
protein coding gene Chr11:79173260-79183673 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019073
protein coding gene Chr11:72670511-72683249 (+)
PWK/PhJ MGP_PWKPhJ_G0017721
protein coding gene Chr11:70594193-70604649 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017511
protein coding gene Chr11:72387167-72397507 (+)
WSB/EiJ MGP_WSBEiJ_G0018002
protein coding gene Chr11:72423127-72433532 (+)



Homology
more
  • Human Ortholog
    MYBBP1A, MYB binding protein 1a
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYBBP1A, MYB binding protein 1a
  • Synonyms
    P160, PAP2, Pol5
  • Links
    NCBI Gene ID: 10514
    neXtProt AC: NX_Q9BQG0
    UniProt: Q9BQG0

  • Chr Location
    17p13.2; chr17:4538897-4555386 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted allele exhibit embryonic lethality before blastocyst formation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000040463 Ensembl Gene Model | MGI Sequence Detail 10414 C57BL/6J ±  kb
    transcript ENSMUST00000045633 Ensembl | MGI Sequence Detail 4358 Not Applicable  
    polypeptide ENSMUSP00000044827 Ensembl | MGI Sequence Detail 1344 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 441
      cDNA 441

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-33871, MGI:2144354, MGI:2144399
    References
    more
    • Summaries
      All 69
      Developmental Gene Expression 7
      Gene Ontology 14
      Phenotypes 19
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:261809 Mayer C, et al., Developmental diversification of cortical inhibitory interneurons. Nature. 2018 Mar 22;555(7697):457-462

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory