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Mybbp1a
Gene Detail
Symbol

Name
ID
Mybbp1a
MYB binding protein (P160) 1a
MGI:106181
Synonyms
p160MBP, p67MBP
Feature Type
protein coding gene
Genetic Map
Chromosome 11
44.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:72441355-72451768 bp, + strand
From VEGA annotation of GRCm38

  10414 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40954  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: MYBBP1A
Gene Tree: Mybbp1a

Human
homologs
MYBBP1A, MYB binding protein (P160) 1a
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 10514
neXtProt AC: NX_Q9BQG0

Human Synonyms: P160, PAP2

Human Chr (Location): 17p13.3; chr17:4538896-4555386 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(10) Targeted(6)
Genomic Mutations involving Mybbp1a (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a targeted allele exhibit embryonic lethality before blastocyst formation.
 
Interactions
Mybbp1a interacts with 94 markers (Mir20b, Mir22, Mir26a-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (377)    Tissues (148)    Images (39)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 377
cDNA source data(440)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mybbp1a ; ZFIN mybbp1a    NEW 
Molecular
reagents
All nucleic(440) cDNA(440)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000006110 (Evidence)
Ensembl Gene Model ENSMUSG00000040463 (Evidence)
Entrez Gene 18432 (Evidence)
UniGene 147946
DFCI TC1573233, TC1605066, TC1780895
NIA Mouse Gene Index U012882
Consensus CDS Project CCDS24986.1
International Mouse Phenotyping Consortium Status Mybbp1a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006110 VEGA Gene Model | MGI Sequence Detail 10414 C57BL/6J ±  kb
transcript OTTMUST00000013809 VEGA | MGI Sequence Detail 4358 Not Applicable 
polypeptide OTTMUSP00000006405 VEGA | MGI Sequence Detail 1344 Not Applicable 

For the selected sequences
All sequences(86) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(72 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR007015 DNA polymerase V
Protein Ontology PR:000010800 myb-binding protein 1A
References
(Earliest) J:31923 Favier D, et al., Detection of proteins that bind to the leucine zipper motif of c-Myb. Oncogene. 1994 Jan;9(1):305-11
(Latest) J:192984 Hochstatter J, et al., Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA. J Biol Chem. 2012 Jul 13;287(29):24365-77
All references(49)
Other
accession IDs
MGD-MRK-33871, MGI:2144354, MGI:2144399

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory