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Etfb Gene Detail
Summary
  • Symbol
    Etfb
  • Name
    electron transferring flavoprotein, beta polypeptide
  • Synonyms
    0610009I16Rik, 2810441H06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:106098
    NCBI Gene: 110826
Location & Maps
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  • Sequence Map
    Chr7:43444108-43457800 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13693 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    ETFB, electron transfer flavoprotein beta subunit
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ETFB, electron transfer flavoprotein beta subunit
    Orthology source: HomoloGene
  • Synonyms
    FP585, MADD
  • Links
    NCBI Gene ID: 2109
    neXtProt AC: NX_P38117

  • Chr Location
    19q13.3; chr19:51345155-51366418 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ETFB associations

Human Disease Mouse Models
       Multiple Acyl-CoA Dehydrogenase Deficiency; MADD   OMIM: 231680
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    11
  • Gene trapped
    9
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023293 VEGA Gene Model | MGI Sequence Detail 13693 C57BL/6J ±  kb
transcript OTTMUST00000056407 VEGA | MGI Sequence Detail 868 Not Applicable  
polypeptide OTTMUSP00000027107 VEGA | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    206 from dbSNP Build 137
  • RFLP
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000007216 electron transfer flavoprotein subunit beta
  • InterPro Domains
    IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal
    IPR012255 Electron transfer flavoprotein, beta subunit
    IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site
    IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Molecular
Reagents
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  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-33785, MGI:1915610, MGI:1920006
References
more
  • Summaries
    All 43
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:32424 White RA, et al., Assignment of Etfdh, Etfb, and Etfa to chromosomes 3, 7, and 13: the mouse homologs of genes responsible for glutaric acidemia type II in human. Genomics. 1996 Apr 1;33(1):131-4
  • Latest
    J:227369 Rhein VF, et al., Human METTL20 methylates lysine residues adjacent to the recognition loop of the electron transfer flavoprotein in mitochondria. J Biol Chem. 2014 Aug 29;289(35):24640-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory