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Slc16a1
Gene Detail
Symbol

Name
ID
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
MGI:106013
Synonyms
MCT1
Feature Type
protein coding gene
Genetic Map
Chromosome 3
45.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:104638668-104658462 bp, + strand
From VEGA annotation of GRCm38

  19795 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20662  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Slc16a1

Human
homologs
Human Homolog SLC16A1, solute carrier family 16 (monocarboxylate transporter), member 1
NCBI Gene ID 6566
neXtProt AC  NX_P53985
Human Synonyms  HHF7, MCT, MCT1, MCT1D
Human Chr (Location)  1p12; chr1:112911847-112956353 (-)  GRCh38
Disease Associations  (3) Diseases Associated with Human SLC16A1
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(8) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes are non-viable, while heterozygous animals are resistant to diet-induced obesity.
 
Interactions
Slc16a1 interacts with 339 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (11 records)
Data Summary: Results (418)    Tissues (142)    Images (38)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 412
RT-PCR 6
cDNA source data(206)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(209) cDNA(207) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022475 (Evidence)
Ensembl Gene ModelENSMUSG00000032902 (Evidence)
Entrez Gene20501 (Evidence)
UniGene9086
DFCITC1573497, TC1752040
DoTSDT.97384801, DT.101191685
Consensus CDS ProjectCCDS17702.1
International Mouse Knockout Project StatusSlc16a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022475 VEGA Gene Model | MGI Sequence Detail 19795 C57BL/6J ±  kb
transcript OTTMUST00000053776 VEGA | MGI Sequence Detail 4426 Not Applicable 
polypeptide OTTMUSP00000025586 VEGA | MGI Sequence Detail 493 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(2) UniProt(15)
Polymorphisms
SNPs within 2kb(89 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011701 Major facilitator superfamily
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
InterPro IPR004743 Monocarboxylate transporter
Protein Ontology PR:000014944 monocarboxylate transporter 1
References
(Earliest) J:20825 Garcia CK, et al., cDNA cloning of the human monocarboxylate transporter 1 and chromosomal localization of the SLC16A1 locus to 1p13.2-p12. Genomics. 1994 Sep 15;23(2):500-3
(Latest) J:214760 Moreau JL, et al., Cited2 is required in trophoblasts for correct placental capillary patterning. Dev Biol. 2014 Aug 1;392(1):62-79
All references(47)
Other
accession IDs
MGD-MRK-33695, MGI:2139849

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory