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Tagln Gene Detail
Summary
  • Symbol
    Tagln
  • Name
    transgelin
  • Synonyms
    SM22, Sm22a, SM22alpha, SM-22 alpha
  • Feature Type
    protein coding gene
  • IDs
    MGI:106012
    NCBI Gene: 21345
  • Gene Overview
    MyGene.info: TAGLN
Location & Maps
more
  • Sequence Map
    Chr9:45929628-45936058 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6431 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 25.36 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TAGLN, transgelin
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TAGLN, transgelin
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SM22, SMCC, TAGLN1, WS3-10
  • Links
    NCBI Gene ID: 6876
    neXtProt AC: NX_Q01995

  • Chr Location
    11q23.2; chr11:117199324-117204792 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 3 alleles in 3 genetic backgrounds
    38 phenotypes from multigenic genotypes
    69 phenotype references
Mice homozygous for targeted mutations in this gene are viable, fertile and phenotypically normal.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 21345 NCBI Gene Model | MGI Sequence Detail 6431 C57BL/6J ±  kb
transcript NM_011526 RefSeq | MGI Sequence Detail 1586 C57BL/6  
polypeptide P37804 UniProt | EBI | MGI Sequence Detail 201 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    40 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    Genomic 3
    cDNA 14
    Primer pair 4
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-33694
References
more
  • Summaries
    All 219
    Developmental Gene Expression 130
    Gene Ontology 3
    Phenotypes 69
  • Earliest
    J:35896 Almendral JM, et al., Expression, cloning and cDNA sequence of a fibroblast serum-regulated gene encoding a putative actin-associated protein (p27). Exp Cell Res. 1989 Apr;181(2):518-30
  • Latest
    J:233746 Wang X, et al., Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung. Dev Biol. 2016 Jun 15;414(2):161-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory