|Human Homolog||ST8SIA1, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1|
|NCBI Gene ID||6489|
|Human Synonyms||GD3S, SIAT8, SIAT8A, SIAT8-A, ST8SiaI|
|Human Chr (Location)||12p12.1-p11.2; chr12:22193391-22334714 (-) GRCh38|
Homozygotes for a targeted allele are behaviorally normal with no signs of aberrant brain histology or demyelination. Homozygotes for a knock-out allele are behaviorally intact with normal nervous tissue morphology and sensitivity to Fas-mediated apoptosis but show impaired repair of damaged nerves.
|Process||cellular response to heat, lipid metabolic process, ...|
|Component||Golgi apparatus, integral component of Golgi membrane, ...|
|Function||alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity, sialyltransferase activity, ...|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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