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Anxa5
Gene Detail
Symbol

Name
ID
Anxa5
annexin A5
MGI:106008
Synonyms
annexin V, Anx5
Feature Type
protein coding gene
Genetic Map
Chromosome 3
17.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(11)
Sequence Map
Chr3:36448926-36475887 bp, - strand
From Ensembl annotation of GRCm38

  26962 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20312  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ANXA5
Gene Tree: Anxa5

Human
homologs
ANXA5, annexin A5
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 308
neXtProt AC: NX_P08758

Human Synonyms: ANX5, ENX2, HEL-S-7, PP4, RPRGL3

Human Chr (Location): 4q27; chr4:121667997-121696992 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ANXA5

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice are viable, fertile, and develop normally. Bone development and maintenance are normal, as are clinical-chemical parameters.
 
Interactions
Anxa5 interacts with 86 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (20 records)
Data Summary: Results (338)    Tissues (104)    Images (59)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 4
RNA in situ 258
In situ reporter (knock in) 22
RT-PCR 54
cDNA source data(181)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA ANXA5 ; Xenbase anxa5 ; ZFIN anxa5a    NEW 
Molecular
reagents
All nucleic(192) Genomic(5) cDNA(182) Primer pair(5)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000027712 (Evidence)
Entrez Gene 11747 (Evidence)
UniGene 1620
DFCI TC1590963, TC1573579, TC1703947
DoTS DT.495192
NIA Mouse Gene Index U023945
Consensus CDS Project CCDS38416.1
International Mouse Phenotyping Consortium Status Anxa5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027712 Ensembl Gene Model | MGI Sequence Detail 26962 C57BL/6J ±  kb
transcript ENSMUST00000029266 Ensembl | MGI Sequence Detail 1721 Not Applicable 
polypeptide ENSMUSP00000029266 Ensembl | MGI Sequence Detail 319 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(1)
Polymorphisms
RFLP(2) : SNPs within 2kb(241 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001464 Annexin
InterPro IPR018502 Annexin repeat
InterPro IPR018252 Annexin repeat, conserved site
InterPro IPR002392 Annexin, type V
InterPro IPR015473 Annexin V
Protein Ontology PR:000004078 annexin A5
References
(Earliest) J:35723 Chepenik KP, et al., Developmental regulation of various annexins in the embryonic palate of the mouse: dexamethasone affects expression of annexin-1. J Craniofac Genet Dev Biol. 1995 Oct-Dec;15(4):171-81
(Latest) J:217593 Garcia TX, et al., RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche. Development. 2014 Dec;141(23):4468-78
All references(74)
Other
accession IDs
MGD-MRK-33688, MGI:2140106

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory