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Mpp1 Gene Detail
Summary
  • Symbol
    Mpp1
  • Name
    membrane protein, palmitoylated
  • Synonyms
    55kDa, C130070C03Rik, erythrocyte protein p55, p55
  • Feature Type
    protein coding gene
  • IDs
    MGI:105941
    NCBI Gene: 17524
  • Gene Overview
    MyGene.info: MPP1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:75109733-75131016 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 38.15 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105941
protein coding gene ChrX:75109733-75131016 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035854
protein coding gene ChrX:70940626-70961858 (-)
A/J MGP_AJ_G0035841
protein coding gene ChrX:71147317-71168182 (-)
AKR/J MGP_AKRJ_G0035762
protein coding gene ChrX:73031372-73055121 (-)
BALB/cJ MGP_BALBcJ_G0035823
protein coding gene ChrX:70171108-70192100 (-)
C3H/HeJ MGP_C3HHeJ_G0035533
protein coding gene ChrX:71418181-71443188 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036353
protein coding gene ChrX:73227692-73248813 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033192
protein coding gene ChrX:70613985-70637030 (-)
CAST/EiJ MGP_CASTEiJ_G0034819
protein coding gene ChrX:56782886-56803985 (-)
CBA/J MGP_CBAJ_G0035506
protein coding gene ChrX:75181682-75203229 (-)
DBA/2J MGP_DBA2J_G0035664
protein coding gene ChrX:70627542-70648487 (-)
FVB/NJ MGP_FVBNJ_G0035605
protein coding gene ChrX:69936560-69957166 (-)
LP/J MGP_LPJ_G0035746
protein coding gene ChrX:71751819-71773032 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035639
protein coding gene ChrX:77786848-77809997 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036379
protein coding gene ChrX:70795301-70826019 (-)
PWK/PhJ MGP_PWKPhJ_G0034516
protein coding gene ChrX:54780562-54802587 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034352
protein coding gene ChrX:57607066-57629565 (-)
WSB/EiJ MGP_WSBEiJ_G0034958
protein coding gene ChrX:70034631-70057673 (-)



Homology
more
  • Human Ortholog
    MPP1, membrane palmitoylated protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MPP1, membrane palmitoylated protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AAG12, DXS552E, EMP55, MRG1, PEMP
  • Links
    NCBI Gene ID: 4354
    neXtProt AC: NX_Q00013
    UniProt: Q00013

  • Chr Location
    Xq28; chrX:154778684-154805527 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 1826
    1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MPP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele display defects in neutrophil polarity and chemotaxis and produce small litters of pups.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 17524 NCBI Gene Model | MGI Sequence Detail 21284 C57BL/6J ±  kb
transcript NM_008621 RefSeq | MGI Sequence Detail 2525 C57BL/6  
polypeptide P70290 UniProt | EBI | MGI Sequence Detail 466 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 110
    Genomic 2
    cDNA 108

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-33620, MGI:2444970
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:31964 Peters LL, et al., Localization of the gene encoding the erythrocyte membrane protein p55 (Mpp1) on the mouse X Chromosome. Mamm Genome. 1996 Mar;7(3):245-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory