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Renbp Gene Detail
Summary
  • Symbol
    Renbp
  • Name
    renin binding protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:105940
    NCBI Gene: 19703
  • Gene Overview
    MyGene.info: RENBP
Location & Maps
more
  • Sequence Map
    ChrX:73922121-73930850 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8730 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    RENBP, renin binding protein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RENBP, renin binding protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RBP, RNBP
  • Links
    NCBI Gene ID: 5973
    neXtProt AC: NX_P51606

  • Chr Location
    Xq28; chrX:153935269-153944780 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Gene trapped
    3
  • Targeted
    2
Mice homozygous for a targeted null mutation exhibit normal function of the renin-angiotensin system and blood pressure regulation; however, abnormalites in urine carbohydrates were noted.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017682 VEGA Gene Model | MGI Sequence Detail 8730 C57BL/6J ±  kb
transcript OTTMUST00000042880 VEGA | MGI Sequence Detail 1418 Not Applicable  
polypeptide OTTMUSP00000019265 VEGA | MGI Sequence Detail 430 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    28 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    Genomic 3
    cDNA 54

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-33619
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:31839 Frattini A, et al., The chromosome localization and the HCF repeats of the human host cell factor gene (HCFC1) are conserved in the mouse homologue. Genomics. 1996 Mar 1;32(2):277-80
  • Latest
    J:188842 Bergfeld AK, et al., Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J Biol Chem. 2012 Aug 17;287(34):28865-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory