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Renbp Gene Detail
Summary
  • Symbol
    Renbp
  • Name
    renin binding protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:105940
    NCBI Gene: 19703
  • Gene Overview
    MyGene.info: RENBP
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:73922121-73930850 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.49 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105940
protein coding gene ChrX:73922121-73930850 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035827
protein coding gene ChrX:69704290-69713013 (-)
A/J MGP_AJ_G0035808
protein coding gene ChrX:69899811-69908308 (-)
AKR/J MGP_AKRJ_G0035733
protein coding gene ChrX:71743484-71753658 (-)
BALB/cJ MGP_BALBcJ_G0035793
protein coding gene ChrX:68926087-68934904 (-)
C3H/HeJ MGP_C3HHeJ_G0035498
protein coding gene ChrX:70180008-70189640 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036323
protein coding gene ChrX:71847401-71856906 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033167
protein coding gene ChrX:68929742-68938511 (-)
CAST/EiJ MGP_CASTEiJ_G0034789
protein coding gene ChrX:55530502-55539085 (-)
CBA/J MGP_CBAJ_G0035473
protein coding gene ChrX:73843474-73854304 (-)
DBA/2J MGP_DBA2J_G0035630
protein coding gene ChrX:69354772-69363500 (-)
FVB/NJ MGP_FVBNJ_G0035574
protein coding gene ChrX:68685311-68702250 (-)
LP/J MGP_LPJ_G0035715
protein coding gene ChrX:70485305-70495226 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035612
protein coding gene ChrX:76395473-76405764 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036345
protein coding gene ChrX:69526438-69535135 (-)
PWK/PhJ MGP_PWKPhJ_G0034488
protein coding gene ChrX:53537603-53546986 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034322
protein coding gene ChrX:56426298-56435429 (-)
WSB/EiJ MGP_WSBEiJ_G0034930
protein coding gene ChrX:68797983-68807966 (-)



Homology
more
  • Human Ortholog
    RENBP, renin binding protein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RENBP, renin binding protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RBP, RNBP
  • Links
    NCBI Gene ID: 5973
    neXtProt AC: NX_P51606
    UniProt: P51606

  • Chr Location
    Xq28; chrX:153935263-153944780 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null mutation exhibit normal function of the renin-angiotensin system and blood pressure regulation; however, abnormalites in urine carbohydrates were noted.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19703 NCBI Gene Model | MGI Sequence Detail 8730 C57BL/6J ±  kb
    transcript NM_023132 RefSeq | MGI Sequence Detail 1434 C57BL/6  
    polypeptide P82343 UniProt | EBI | MGI Sequence Detail 430 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 58
      Genomic 3
      cDNA 55

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-33619
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 6
    • Earliest
      J:31839 Frattini A, et al., The chromosome localization and the HCF repeats of the human host cell factor gene (HCFC1) are conserved in the mouse homologue. Genomics. 1996 Mar 1;32(2):277-80
    • Latest
      J:188842 Bergfeld AK, et al., Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J Biol Chem. 2012 Aug 17;287(34):28865-81

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory