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Rab5b
Gene Detail
 Symbol
Name
ID
Rab5b
RAB5B, member RAS oncogene family
MGI:105938
Synonyms C030027M18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 10
77.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr10:128677193-128696268 bp, - strand
From Ensembl annotation of GRCm38

  19076 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:104027  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab5b

Human
homologs
Human Homolog RAB5B, RAB5B, member RAS oncogene family
NCBI Gene ID 5869
neXtProt AC  NX_P61020
Human Chr (Location)  12q13; chr12:55973913-55996683 (+)  GRCh38
Alleles
and
phenotypes
All alleles(29) : Targeted(3) Gene trapped(26)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process antigen processing and presentation, endosome organization, ...
Component endocytic vesicle, endosome, ...
Function GDP binding, GTPase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (42)    Tissues (28)    Images (13)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 42
cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(7) cDNA(6) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000000711 (Evidence)
Entrez Gene19344 (Evidence)
DFCITC1582769, TC1587360, TC1649828
DoTSDT.110721989, DT.482289, DT.55182051, DT.87057400, DT.97391540, DT.99850844
NIA Mouse Gene IndexU032371, U165524
Consensus CDS ProjectCCDS24287.1
International Mouse Knockout Project StatusRab5b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000000711 Ensembl Gene Model | MGI Sequence Detail 19076 C57BL/6J ±  kb
transcript ENSMUST00000000727 Ensembl | MGI Sequence Detail 3166 Not Applicable 
polypeptide ENSMUSP00000000727 Ensembl | MGI Sequence Detail 215 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(5) UniProt(4)
Polymorphisms RFLP(2) : SNPs within 2kb(128 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013634 ras-related protein Rab-5B
References (Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:186386 Welliver TP, et al., A growth factor signaling cascade confined to circular ruffles in macrophages. Biol Open. 2012;1:754-760
All references(39)
Other
accession IDs
MGD-MRK-33617, MGI:2444434

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory