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Rab5b Gene Detail
Summary
  • Symbol
    Rab5b
  • Name
    RAB5B, member RAS oncogene family
  • Synonyms
    C030027M18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:105938
    NCBI Gene: 19344
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:128513044-128532133 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 77.13 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    128 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105938
protein coding gene Chr10:128511980-128532160 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0017852
protein coding gene Chr10:127124961-127146141 (-)
AKR/J MGP_AKRJ_G0017815
protein coding gene Chr10:130843239-130862075 (-)
BALB/cJ MGP_BALBcJ_G0017816
protein coding gene Chr10:127492809-127512894 (-)
C3H/HeJ MGP_C3HHeJ_G0017639
protein coding gene Chr10:131010083-131033221 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018271
protein coding gene Chr10:136919234-136938656 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015949
protein coding gene Chr10:121040883-121047000 (-)
CAST/EiJ MGP_CASTEiJ_G0017200
protein coding gene Chr10:131731527-131754776 (-)
CBA/J MGP_CBAJ_G0017609
protein coding gene Chr10:142497857-142526775 (-)
DBA/2J MGP_DBA2J_G0017715
protein coding gene Chr10:126186459-126207928 (-)
FVB/NJ MGP_FVBNJ_G0017710
protein coding gene Chr10:125102011-125117571 (-)
LP/J MGP_LPJ_G0017789
protein coding gene Chr10:133036561-133055773 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017738
protein coding gene Chr10:145071196-145093131 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018311
protein coding gene Chr10:130949504-130969345 (-)
PWK/PhJ MGP_PWKPhJ_G0016985
protein coding gene Chr10:126444786-126452370 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016774
protein coding gene Chr10:130060772-130080023 (-)
WSB/EiJ MGP_WSBEiJ_G0017259
protein coding gene Chr10:131169391-131189498 (-)



Homology
more
  • Human Ortholog
    RAB5B, RAB5B, member RAS oncogene family
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB5B, RAB5B, member RAS oncogene family
  • Links
    NCBI Gene ID: 5869
    neXtProt AC: NX_P61020
    UniProt: P61020

  • Chr Location
    12q13.2; chr12:55973913-55996683 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000000711 Ensembl Gene Model | MGI Sequence Detail 19090 C57BL/6J ±  kb
transcript ENSMUST00000000727 Ensembl | MGI Sequence Detail 3180 Not Applicable  
polypeptide ENSMUSP00000000727 Ensembl | MGI Sequence Detail 215 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 7
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-33617, MGI:2444434
References
more
  • Summaries
    All 46
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory