Rab5b
Gene Detail

Symbol Name ID

Rab5b RAB5B, member RAS oncogene family MGI:105938

Synonyms

C030027M18Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 10

77.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr10:128677193-128696268 bp, - strand From Ensembl annotation of GRCm38   19076 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:104027  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab5b

Human homologs

Human Homolog		RAB5B, RAB5B, member RAS oncogene family
NCBI Gene ID		5869
neXtProt AC		NX_P61020
Human Chr (Location)		12q13; chr12:56367697-56390467 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(28) : Targeted(2) Gene trapped(26)

Gene Ontology (GO) classifications

All GO classifications: (18 annotations)

Process	endosome organization, GTP catabolic process, ...
Component	endocytic vesicle, endosome, ...
Function	GDP binding, GTPase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (42)    Tissues (28)    Images (13)
Theiler Stages: 19, 23, 28

Assay Type	Results
RNA in situ	42

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) cDNA(6) Other(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000000711 (Evidence)
Entrez Gene	19344 (Evidence)
DFCI	TC1582769, TC1587360, TC1649828
DoTS	DT.482289, DT.55182051, DT.87057400, DT.97391540, DT.99850844
NIA Mouse Gene Index	U032371, U165524
Consensus CDS Project	CCDS24287.1
International Mouse Knockout Project Status	Rab5b

Sequences

Length	Strain/Species
genomic	ENSMUSG00000000711	Ensembl Gene Model | MGI Sequence Detail	19076	C57BL/6J
transcript	ENSMUST00000000727	Ensembl | MGI Sequence Detail	3166	Not Applicable
polypeptide	ENSMUSP00000000727	Ensembl | MGI Sequence Detail	215	Not Applicable

All sequences(40) RefSeq(3) UniProt(4)

Polymorphisms

RFLP(2) : SNPs(36 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013634	ras-related protein Rab-5B

References

(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:186386 Welliver TP, et al., A growth factor signaling cascade confined to circular ruffles in macrophages. Biol Open. 2012;1:754-760
All references(38)

Other accession IDs

MGD-MRK-33617, MGI:2444434