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Cdo1 Gene Detail
Summary
  • Symbol
    Cdo1
  • Name
    cysteine dioxygenase 1, cytosolic
  • Synonyms
    1300002L19Rik, Cdo, D18Ucla3
  • Feature Type
    protein coding gene
  • IDs
    MGI:105925
    NCBI Gene: 12583
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:46713205-46728342 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 24.75 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105925
protein coding gene Chr18:46713205-46728582 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024411
protein coding gene Chr18:45531148-45550480 (-)
A/J MGP_AJ_G0024378
protein coding gene Chr18:43892857-43910621 (-)
AKR/J MGP_AKRJ_G0024347
protein coding gene Chr18:45093165-45108225 (-)
BALB/cJ MGP_BALBcJ_G0024378
protein coding gene Chr18:43989720-44009115 (-)
C3H/HeJ MGP_C3HHeJ_G0024145
protein coding gene Chr18:45181795-45197865 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024822
protein coding gene Chr18:47129779-47146591 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022257
protein coding gene Chr18:43708025-43723399 (-)
CAST/EiJ MGP_CASTEiJ_G0023619
protein coding gene Chr18:45132197-45149466 (-)
CBA/J MGP_CBAJ_G0024114
protein coding gene Chr18:48407690-48428506 (-)
DBA/2J MGP_DBA2J_G0024244
protein coding gene Chr18:43495909-43514819 (-)
FVB/NJ MGP_FVBNJ_G0024210
protein coding gene Chr18:43062417-43080379 (-)
LP/J MGP_LPJ_G0024328
protein coding gene Chr18:45598254-45613349 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024241
protein coding gene Chr18:49772149-49796315 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024869
protein coding gene Chr18:45013103-45028197 (-)
PWK/PhJ MGP_PWKPhJ_G0023363
protein coding gene Chr18:43643761-43659024 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023168
protein coding gene Chr18:45154029-45169021 (-)
WSB/EiJ MGP_WSBEiJ_G0023682
protein coding gene Chr18:44908663-44927202 (-)



Homology
more
  • Human Ortholog
    CDO1, cysteine dioxygenase type 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CDO1, cysteine dioxygenase type 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDO-I
  • Links
    NCBI Gene ID: 1036
    neXtProt AC: NX_Q16878
    UniProt: Q16878

  • Chr Location
    5q22.3; chr5:115804733-115816708 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    36 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a deletion of this gene show increased preweaning mortality, lower body weight, behavioral defects, skeletal defects, homeostatic and reproductive defects.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033022 Ensembl Gene Model | MGI Sequence Detail 15138 C57BL/6J ±  kb
    transcript ENSMUST00000035804 Ensembl | MGI Sequence Detail 1530 Not Applicable  
    polypeptide ENSMUSP00000046517 Ensembl | MGI Sequence Detail 200 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 246
      cDNA 240
      Primer pair 4
      Other 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-33603, MGD-MRK-5037, MGI:1923528, MGI:91193
    References
    more
    • Summaries
      All 58
      Developmental Gene Expression 9
      Gene Ontology 4
      Phenotypes 5
    • Earliest
      J:15567 Warden CH, et al., Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov;18(2):295-307
    • Latest
      J:242713 Ikeda Y, et al., Fgfr2 is integral for bladder mesenchyme patterning and function. Am J Physiol Renal Physiol. 2017 Apr 01;312(4):F607-F618

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory