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Adam9
Gene Detail
Symbol

Name
ID
Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
MGI:105376
Synonyms
MDC9, MDC9, mKIAA0021, Mltng, Mltng
Feature Type
protein coding gene
Genetic Map
Chromosome 8
13.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:24949611-25016922 bp, - strand
From Ensembl annotation of GRCm38

  67312 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20824  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Adam9

Human
homologs
Human Homolog ADAM9, ADAM metallopeptidase domain 9
NCBI Gene ID 8754
neXtProt AC  NX_Q13443
Human Synonyms  CORD9, MCMP, MDC9, Mltng
Human Chr (Location)  8p11.22; chr8:38996986-39105261 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ADAM9
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(6) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene does not result in a phenotype.
 
Interactions
Adam9 interacts with 245 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (49 annotations)
Process activation of MAPKK activity, cell adhesion, ...
Component basolateral plasma membrane, cell surface, ...
Function collagen binding, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (29)    Tissues (20)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 19
RNA in situ 9
RT-PCR 1
cDNA source data(131)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(133) cDNA(131) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000031555 (Evidence)
Entrez Gene11502 (Evidence)
UniGene28908
DFCITC1601301, TC1574038
DoTSDT.94190555, DT.533295
NIA Mouse Gene IndexU029657
EC3.4.24.-
International Mouse Knockout Project StatusAdam9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031555 Ensembl Gene Model | MGI Sequence Detail 67312 C57BL/6J ±  kb
transcript ENSMUST00000084035 Ensembl | MGI Sequence Detail 3985 Not Applicable 
polypeptide ENSMUSP00000081048 Ensembl | MGI Sequence Detail 845 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(6) UniProt(7)
Polymorphisms
RFLP(1) : SNPs within 2kb(326 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006586 ADAM, cysteine-rich
InterPro IPR001762 Blood coagulation inhibitor, Disintegrin
InterPro IPR018358 Disintegrin, conserved site
InterPro IPR013032 EGF-like, conserved site
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR024079 Metallopeptidase, catalytic domain
InterPro IPR001590 Peptidase M12B, ADAM/reprolysin
InterPro IPR002870 Peptidase M12B, propeptide
Protein Ontology PR:000003725 disintegrin and metalloproteinase domain-containing protein 9
References
(Earliest) J:30468 Weskamp G, et al., A family of cellular proteins related to snake venom disintegrins. Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2748-51
(Latest) J:213829 Bard-Chapeau EA, et al., Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects. PLoS One. 2014;9(2):e89397
All references(60)
Other
accession IDs
MGD-MRK-33045, MGI:2142696

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory