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Sstr4
Gene Detail
Symbol

Name
ID
Sstr4
somatostatin receptor 4
MGI:105372
Synonyms
Smstr4, sst4
Feature Type
protein coding gene
Genetic Map
Chromosome 2
73.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr2:148395344-148396767 bp, + strand
From VEGA annotation of GRCm38

  1424 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20286  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: somatostatin receptor
Gene Tree: Sstr4

Human
homologs
Human Homolog SSTR4, somatostatin receptor 4
NCBI Gene ID 6754
neXtProt AC  NX_P31391
Human Synonyms  SS4R, SS-4-R, SS4-R
Human Chr (Location)  20p11.2; chr20:23035420-23036677 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygote null mice have increased susceptibility to inflammation, delayed type hypersensitivity, hyperalgesia and airway hypersensitivity.
 
Interactions
Sstr4 interacts with 122 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (31 annotations)
Process arachidonic acid metabolic process, behavior, ...
Component cytoplasm, integral component of membrane, ...
Function G-protein coupled receptor activity, neuropeptide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (165)    Tissues (66)    Images (11)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 27
RT-PCR 138
cDNA source data(7)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) Genomic(3) cDNA(7) Primer pair(3)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000015711 (Evidence)
Ensembl Gene ModelENSMUSG00000037014 (Evidence)
Entrez Gene20608 (Evidence)
UniGene35324
DFCITC1673196, TC1587823
DoTSDT.91552020, DT.55171894, DT.110690478
NIA Mouse Gene IndexU002597
Consensus CDS ProjectCCDS38260.1
International Mouse Knockout Project StatusSstr4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015711 VEGA Gene Model | MGI Sequence Detail 1424 C57BL/6J ±  kb
transcript OTTMUST00000037330 VEGA | MGI Sequence Detail 1424 Not Applicable 
polypeptide OTTMUSP00000016722 VEGA | MGI Sequence Detail 385 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(1)
Polymorphisms
PCR(1) : SNPs within 2kb(20 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001512 Somatostatin receptor 4
InterPro IPR000586 Somatostatin receptor family
Protein Ontology PR:000001671 somatostatin receptor type 4
References
(Earliest) J:31780 Schwabe W, et al., Isolation and characterization of the mouse (Mus musculus) somatostatin receptor type-4-encoding gene (mSSTR4). Gene. 1996 Feb 12;168(2):233-5
(Latest) J:185665 Guo Z, et al., Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
All references(47)
Other
accession IDs
MGD-MRK-33041

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory