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Rad23a
Gene Detail
Symbol

Name
ID
Rad23a
RAD23a homolog (S. cerevisiae)
MGI:105126
Feature Type
protein coding gene
Genetic Map
Chromosome 8
41.20 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr8:84834019-84840665 bp, - strand
From VEGA annotation of GRCm38

  6647 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48322  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Rad23a

Human
homologs
Human Homolog RAD23A, RAD23 homolog A (S. cerevisiae)
NCBI Gene ID 5886
neXtProt AC  NX_P54725
Human Synonyms  HHR23A, HR23A
Human Chr (Location)  19p13.2; chr19:12945814-12953643 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(7) Targeted(5)
Incidental mutations (data from APF )
 
Mice with a targeted disruption of this gene show no obvious phenotype.
 
Interactions
Rad23a interacts with 95 markers (Mir22, Mir92-2, Mir103-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cellular response to DNA damage stimulus, DNA repair, ...
Component cytoplasm, nucleus, ...
Function damaged DNA binding, polyubiquitin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (2)    Tissues (2)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 2
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) Genomic(1) cDNA(13) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000022270 (Evidence)
Ensembl Gene ModelENSMUSG00000003813 (Evidence)
Entrez Gene19358 (Evidence)
NIA Mouse Gene IndexU030040
Consensus CDS ProjectCCDS40414.1
International Mouse Knockout Project StatusRad23a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022270 VEGA Gene Model | MGI Sequence Detail 6647 C57BL/6J ±  kb
transcript OTTMUST00000053034 VEGA | MGI Sequence Detail 1842 Not Applicable 
polypeptide OTTMUSP00000025195 VEGA | MGI Sequence Detail 363 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(6) UniProt(6)
Polymorphisms
SNPs within 2kb(48 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006636 Heat shock chaperonin-binding
InterPro IPR009060 UBA-like
InterPro IPR000626 Ubiquitin
InterPro IPR000449 Ubiquitin-associated/translation elongation factor EF1B, N-terminal
InterPro IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote
InterPro IPR004806 UV excision repair protein Rad23
InterPro IPR015360 XPC-binding domain
Protein Ontology PR:000013669 UV excision repair protein RAD23 homolog A
References
(Earliest) J:30878 van der Spek PJ, et al., Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23. Genomics. 1996 Jan 1;31(1):20-7
(Latest) J:185050 Bergink S, et al., Recognition of DNA damage by XPC coincides with disruption of the XPC-RAD23 complex. J Cell Biol. 2012 Mar 19;196(6):681-8
All references(34)
Other
accession IDs
MGD-MRK-32167, MGI:1916893, MGI:2142661

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory