About   Help   FAQ
Rad23a Gene Detail
Summary
  • Symbol
    Rad23a
  • Name
    RAD23 homolog A, nucleotide excision repair protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:105126
    NCBI Gene: 19358
  • Gene Overview
    MyGene.info: RAD23A
Location & Maps
more
  • Sequence Map
    Chr8:84834019-84840665 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6647 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 41.20 cM, cytoband C3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    RAD23A, RAD23 homolog A, nucleotide excision repair protein
  • Vertebrate Orthologs
    7
  • Human Ortholog
    RAD23A, RAD23 homolog A, nucleotide excision repair protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HHR23A, HR23A
  • Links
    NCBI Gene ID: 5886
    neXtProt AC: NX_P54725

  • Chr Location
    19p13.2; chr19:12945814-12953643 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 3 alleles in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    34 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Gene trapped
    7
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Rad23a
  • Incidental Mutations
    APF
Mice with a targeted disruption of this gene show no obvious phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022270 VEGA Gene Model | MGI Sequence Detail 6647 C57BL/6J ±  kb
transcript OTTMUST00000053034 VEGA | MGI Sequence Detail 1842 Not Applicable  
polypeptide OTTMUSP00000025195 VEGA | MGI Sequence Detail 363 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    48 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 1
    cDNA 13
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-32167, MGI:1916893, MGI:2142661
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 34
  • Earliest
    J:30878 van der Spek PJ, et al., Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23. Genomics. 1996 Jan 1;31(1):20-7
  • Latest
    J:185050 Bergink S, et al., Recognition of DNA damage by XPC coincides with disruption of the XPC-RAD23 complex. J Cell Biol. 2012 Mar 19;196(6):681-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory