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Tnni1 Gene Detail
Summary
  • Symbol
    Tnni1
  • Name
    troponin I, skeletal, slow 1
  • Synonyms
    2700018B22Rik, ssTnI
  • Feature Type
    protein coding gene
  • IDs
    MGI:105073
    NCBI Gene: 21952
  • Gene Overview
    MyGene.info: TNNI1
Location & Maps
more
  • Sequence Map
    Chr1:135779434-135810989 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      31556 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 59.28 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    TNNI1, troponin I1, slow skeletal type
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TNNI1, troponin I1, slow skeletal type
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SSTNI, TNN1
  • Links
    NCBI Gene ID: 7135
    neXtProt AC: NX_P19237

  • Chr Location
    1q31.3; chr1:201403767-201421746 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2462
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TNNI1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    2
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    3 involving Tnni1
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033121 VEGA Gene Model | MGI Sequence Detail 31556 C57BL/6J ±  kb
transcript OTTMUST00000082800 VEGA | MGI Sequence Detail 1105 Not Applicable  
polypeptide OTTMUSP00000044424 VEGA | MGI Sequence Detail 187 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    571 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000016504 troponin I, slow skeletal muscle
  • InterPro Domains
    IPR001978 Troponin
Molecular
Reagents
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  • All nucleic 128
    cDNA 126
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-32113, MGI:1917282, MGI:2138320
References
more
  • Summaries
    All 61
    Developmental Gene Expression 28
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:31429 Koppe RI, et al., cDNA clone and expression analysis of rodent fast and slow skeletal muscle troponin I mRNAs. J Biol Chem. 1989 Aug 25;264(24):14327-33
  • Latest
    J:229253 Spies N, et al., Constraint and divergence of global gene expression in the mammalian embryo. Elife. 2015;4:e05538

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory