About   Help   FAQ
Rab22a
Gene Detail
Symbol

Name
ID
Rab22a
RAB22A, member RAS oncogene family
MGI:105072
Synonyms
3732413A17Rik, E130120E14Rik, Rab22
Feature Type
protein coding gene
Genetic Map
Chromosome 2
97.26 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:173659760-173707343 bp, + strand
From VEGA annotation of GRCm38

  47584 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10782  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: RAB22A
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab22a

Human
homologs
RAB22A, RAB22A, member RAS oncogene family
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 57403
neXtProt AC: NX_Q9UL26

Human Chr (Location): 20q13.32; chr20:58309715-58367507 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(9) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Rab22a interacts with 455 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process endocytosis, intracellular protein transport, ...
Component actin cytoskeleton, cell projection, ...
Function GDP binding, GTPase activity, ...
External Resources: FuncBase
Expression
cDNA source data(115)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rab22a ; ZFIN rab22a    NEW 
Molecular
reagents
All nucleic(117) cDNA(117)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000016371 (Evidence)
Ensembl Gene Model ENSMUSG00000027519 (Evidence)
Entrez Gene 19334 (Evidence)
UniGene 275304
DFCI TC1645537, TC1628232, TC1578364
DoTS DT.101400330, DT.531954, DT.489291, DT.110667144
NIA Mouse Gene Index U002916
PDB 1YVD, 1Z0J
Consensus CDS Project CCDS38352.1
International Mouse Phenotyping Consortium Status Rab22a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016371 VEGA Gene Model | MGI Sequence Detail 47584 C57BL/6J ±  kb
transcript OTTMUST00000039406 VEGA | MGI Sequence Detail 7155 Not Applicable 
polypeptide OTTMUSP00000017605 VEGA | MGI Sequence Detail 194 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(2) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(261 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013595 ras-related protein Rab-22A
References
(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:175007 Woller B, et al., Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22. Biochim Biophys Acta. 2011 Jun;1813(6):1198-210
All references(41)
Other
accession IDs
MGD-MRK-32112, MGI:1914673, MGI:1925122, MGI:2139037, MGI:2139342, MGI:2139386

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory