Rab22a
Gene Detail

Symbol Name ID

Rab22a RAB22A, member RAS oncogene family MGI:105072

Synonyms

3732413A17Rik, E130120E14Rik, Rab22

Feature Type

protein coding gene

Genetic Map

Chromosome 2

97.26 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr2:173659760-173707343 bp, + strand From VEGA annotation of GRCm38   47584 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10782  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab22a

Human homologs

Human Homolog		RAB22A, RAB22A, member RAS oncogene family
NCBI Gene ID		57403
neXtProt AC		NX_Q9UL26
Human Chr (Location)		20q13.32; chr20:56884771-56942563 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(11) : Targeted(2) Gene trapped(9)

Gene Ontology (GO) classifications

All GO classifications: (19 annotations)

Process	endocytosis, GTP catabolic process, ...
Component	actin cytoskeleton, cell projection, ...
Function	GDP binding, GTPase activity, ...

External Resources: FuncBase

Expression

cDNA source data(114)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(116) cDNA(116)
Microarray probesets(9)

Other database links

VEGA Gene Model	OTTMUSG00000016371 (Evidence)
Ensembl Gene Model	ENSMUSG00000027519 (Evidence)
Entrez Gene	19334 (Evidence)
UniGene	275304
DFCI	TC1578364, TC1628232, TC1645537
DoTS	DT.101400330, DT.110667144, DT.489291, DT.531954
NIA Mouse Gene Index	U002916
PDB	1YVD, 1Z0J
Consensus CDS Project	CCDS38352.1
International Mouse Knockout Project Status	Rab22a

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016371	VEGA Gene Model | MGI Sequence Detail	47584	C57BL/6J
transcript	OTTMUST00000039406	VEGA | MGI Sequence Detail	7155	Not Applicable
polypeptide	OTTMUSP00000017605	VEGA | MGI Sequence Detail	194	Not Applicable

All sequences(57) RefSeq(2) UniProt(5)

Polymorphisms

RFLP(1) : SNPs(88 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013595	ras-related protein Rab-22A

References

(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:175007 Woller B, et al., Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22. Biochim Biophys Acta. 2011 Jun;1813(6):1198-210
All references(41)

Other accession IDs

MGD-MRK-32112, MGI:1914673, MGI:1925122, MGI:2139037, MGI:2139342, MGI:2139386