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Rab4b Gene Detail
Summary
  • Symbol
    Rab4b
  • Name
    RAB4B, member RAS oncogene family
  • Synonyms
    1500031G17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:105071
    NCBI Gene: 19342
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:26867858-26878308 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 15.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    305 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105071
 protein coding gene Chr7:26867849-26878321 (-)
129S1/SvImJ ENSMUSG00200041477
 protein coding gene Chr7:16664762-16675232 (-)
A/J ENSMUSG00195049881
 protein coding gene Chr7:19309924-19320403 (-)
AKR/J ENSMUSG00220049213
 protein coding gene Chr7:25165573-25176054 (+)
BALB/cJ ENSMUSG00180052328
 protein coding gene Chr7:17375117-17385590 (-)
C3H/HeJ ENSMUSG00175049563
 protein coding gene Chr7:18425961-18436437 (-)
C57BL/6NJ ENSMUSG00215054727
 protein coding gene Chr7:16556998-16567478 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029399
 protein coding gene Chr7:26419355-26429555 (-)
CAST/EiJ ENSTCUG00005047217
 protein coding gene Chr7:18363556-18373932 (-)
CBA/J ENSMUSG00210052221
 protein coding gene Chr7:17611471-17621948 (-)
DBA/2J ENSMUSG00185050157
 protein coding gene Chr7:20718861-20729339 (-)
FVB/NJ ENSMUSG00205050511
 protein coding gene Chr7:17400646-17411102 (-)
JF1/MsJ ENSUMUG00000047638
 protein coding gene Chr7:25151252-25161662 (-)
LP/J ENSMUSG00230053445
 protein coding gene Chr7:25890744-25901212 (-)
NOD/ShiLtJ ENSMUSG00190032407
 protein coding gene Chr7:17053109-17063560 (-)
NZO/HlLtJ ENSMUSG00225024828
 protein coding gene Chr7:24767561-24778038 (-)
PWK/PhJ ENSLUMG00010035775
 protein coding gene Chr7:17082487-17092901 (-)
SPRET/EiJ ENSMSPG00010050482
 protein coding gene Chr7:16469207-16475357 (-)
WSB/EiJ ENSIUOG00005050825
 protein coding gene Chr7:11310178-11320648 (-)



Homology
more
  • Human Ortholog
    RAB4B, RAB4B, member RAS oncogene family
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB4B, RAB4B, member RAS oncogene family
  • Links
    NCBI Gene ID: 53916
    UniProt: P61018

  • Chr Location
    19q13.2; chr19:40778195-40798690 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    38
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    650
  • Tissues
    6
  • cDNA Data
    72
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19342 NCBI Gene Model | MGI Sequence Detail 10451 C57BL/6J ±  kb
    transcript NM_029391 RefSeq | MGI Sequence Detail 1170 ZRU/MplStud  
    polypeptide Q91ZR1 UniProt | EBI | MGI Sequence Detail 213 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 73
      cDNA 73

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-32110, MGI:1922952
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 2
      Gene Ontology 11
      Phenotypes 8
    • Earliest
      J:30578 Barbosa MD, et al., The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics. 1995 Dec 10;30(3):439-44
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory