Rab4b
Gene Detail

Symbol

Name
ID

Rab4b
RAB4B, member RAS oncogene family
MGI:105071

Synonyms

1500031G17Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 7
15.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:27168424-27178896 bp, - strand From VEGA annotation of GRCm38   10473 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate
homology

HomoloGene:100632  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab4b

Human
homologs

Human Homolog		RAB4B, RAB4B, member RAS oncogene family
NCBI Gene ID		53916
neXtProt AC		NX_P61018
Human Chr (Location)		19q13.2; chr19:40778219-40796944 (+)  GRCh38

Mutations,
alleles, and
phenotypes

All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )

Interactions

Rab4b interacts with 87 markers (Mir9-1, Mir9-2, Mir9-3, ...)

View All

Gene Ontology
(GO)
classifications

All GO classifications: (20 annotations)

Process	glucose import, intracellular protein transport, ...
Component	endosome, insulin-responsive compartment, ...
Function	GTPase activity, GTP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)

Data Summary: Results (53)    Tissues (6)    Images (23)    Tissue x Stage Matrix (view)

Assay Type	Results
RNA in situ	53

cDNA source data(71)
External Resources: Allen Institute   GEO   Expression Atlas

Molecular
reagents

All nucleic(72) cDNA(72)
Microarray probesets(3)

Other database
links

VEGA Gene Model	OTTMUSG00000022790 (Evidence)
Ensembl Gene Model	ENSMUSG00000053291 (Evidence)
Entrez Gene	19342 (Evidence)
UniGene	482114
DFCI	TC1575797
DoTS	DT.493015, DT.101711965, DT.101366797
Consensus CDS Project	CCDS21012.1
International Mouse Knockout Project Status	Rab4b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022790	VEGA Gene Model | MGI Sequence Detail	10473	C57BL/6J
transcript	OTTMUST00000054742	VEGA | MGI Sequence Detail	1192	Not Applicable
polypeptide	OTTMUSP00000026157	VEGA | MGI Sequence Detail	213	Not Applicable

All sequences(45) RefSeq(6) UniProt(4)

Polymorphisms

RFLP(1) : SNPs within 2kb(33 from dbSNP Build 137)

Protein-related
information

Resource	ID	Description
InterPro	IPR027417	P-loop containing nucleoside triphosphate hydrolase
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013632	ras-related protein Rab-4B

References

(Earliest) J:30578 Barbosa MD, et al., The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics. 1995 Dec 10;30(3):439-44
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Other
accession IDs

MGD-MRK-32110, MGI:1922952