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Rab4b Gene Detail
Summary
  • Symbol
    Rab4b
  • Name
    RAB4B, member RAS oncogene family
  • Synonyms
    1500031G17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:105071
    NCBI Gene: 19342
Location & Maps
more
  • Sequence Map
    Chr7:27168424-27178896 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      10473 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 15.84 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RAB4B, RAB4B, member RAS oncogene family
  • Vertebrate Orthologs
    7
  • Human Ortholog
    RAB4B, RAB4B, member RAS oncogene family
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 53916
    neXtProt AC: NX_P61018

  • Chr Location
    19q13.2; chr19:40778219-40796944 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    53
  • Tissues
    6
  • cDNA Data
    71
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022790 VEGA Gene Model | MGI Sequence Detail 10473 C57BL/6J ±  kb
transcript OTTMUST00000054742 VEGA | MGI Sequence Detail 1192 Not Applicable  
polypeptide OTTMUSP00000026157 VEGA | MGI Sequence Detail 213 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    33 from dbSNP Build 142
  • RFLP
    1
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013632 ras-related protein Rab-4B
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
less
  • All nucleic 72
    cDNA 72

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-32110, MGI:1922952
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:30578 Barbosa MD, et al., The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics. 1995 Dec 10;30(3):439-44
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory