Tnni2
Gene Detail

Symbol Name ID

Tnni2 troponin I, skeletal, fast 2 MGI:105070

Feature Type

protein coding gene

Genetic Map

Chromosome 7

87.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:142441808-142444410 bp, + strand From VEGA annotation of GRCm38   2603 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:37752  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 6 zebrafish

Gene Tree: Tnni2

Human homologs

Human Homolog		TNNI2, troponin I type 2 (skeletal, fast)
NCBI Gene ID		7136
neXtProt AC		NX_P48788
Human Synonyms		AMCD2B, DA2B, FSSV, fsTnI
Human Chr (Location)		11p15.5; chr11:1860233-1862910 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TNNI2

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	positive regulation of transcription, DNA-dependent, regulation of muscle contraction, ...
Component	nucleus, troponin complex
Function	actin binding, metal ion binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (22 records)
Data Summary: Results (48)    Tissues (15)    Images (14)
Theiler Stages: 17, 20, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	10
Northern blot	2
RT-PCR	36

cDNA source data(102)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(106) cDNA(103) Primer pair(3)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000018792 (Evidence)
Ensembl Gene Model	ENSMUSG00000031097 (Evidence)
Entrez Gene	21953 (Evidence)
UniGene	39469
DFCI	TC1574730
DoTS	DT.87069868
NIA Mouse Gene Index	U008982
Consensus CDS Project	CCDS40192.1
International Mouse Knockout Project Status	Tnni2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000018792	VEGA Gene Model | MGI Sequence Detail	2603	C57BL/6J
transcript	OTTMUST00000045244	VEGA | MGI Sequence Detail	668	Not Applicable
polypeptide	OTTMUSP00000020349	VEGA | MGI Sequence Detail	190	Not Applicable

All sequences(33) RefSeq(2) UniProt(3)

Polymorphisms

RFLP(1) : SNPs(20 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001978	Troponin
Protein Ontology	PR:000016505	troponin I, fast skeletal muscle

References

(Earliest) J:31429 Koppe RI, et al., cDNA clone and expression analysis of rodent fast and slow skeletal muscle troponin I mRNAs. J Biol Chem. 1989 Aug 25;264(24):14327-33
(Latest) J:193107 Jin C, et al., Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis. Dev Biol. 2013 Feb 1;374(1):96-107
All references(48)

Other accession IDs

MGD-MRK-32109